Detection of RHDVa on the Iberian Peninsula: isolation of an RHDVa strain from a Spanish rabbitry

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• 作者：Joana Abrantes (1) (2)
  Ana M. Lopes (1) (2) (3)
  Kevin P. Dalton (4)
  Francisco Parra (4)
  Pedro J. Esteves (1) (5)
  
• 刊名：Archives of Virology
• 出版年：2014
• 出版时间：February 2014
• 年：2014
• 卷：159
• 期：2
• 页码：321-326
• 全文大小：241 KB
• 作者单位：Joana Abrantes (1) (2)
  Ana M. Lopes (1) (2) (3)
  Kevin P. Dalton (4)
  Francisco Parra (4)
  Pedro J. Esteves (1) (5)
  
  1. CIBIO/UP, Centro de Investiga莽茫o em Biodiversidade e Recursos Gen茅ticos/Universidade do Porto, InBio, Laborat贸rio Associado, Campus Agr谩rio de Vair茫o, Rua Padre Armando Quintas, nr. 7, 4485-661, Vair茫o, Portugal
  2. INSERM, U892, Universit茅 de Nantes, Nantes, France
  3. Departamento de Zoologia e Antropologia, Faculdade de Ci锚ncias da Universidade do Porto, Porto, Portugal
  4. Departamento de Bioqu铆mica y Biolog铆a Molecular, Instituto Universitario de Biotecnolog铆a de Asturias, Universidad de Oviedo, C/Fernando Bongera s/n, 33006, Oviedo, Spain
  5. CITS, Centro de Investiga莽茫o em Tecnologias da Sa煤de, IPSN, CESPU, Gandra, Portugal
  
• ISSN：1432-8798

文摘

Rabbit haemorrhagic disease virus (RHDV), genus Lagovirus, family Caliciviridae, causes a large number of deaths in wild and domestic adult European rabbits (Oryctolagus cuniculus). The first documented outbreak dates from 1984 in China, but the virus rapidly dispersed worldwide. In 1997, an antigenic variant was detected in Italy and designated RHDVa. Despite causing symptoms similar to those caused by classic RHDV strains, marked antigenic and genetic differences exist. In some parts of Europe, RHDVa is replacing classic strains. Here, we report the presence of RHDVa on the Iberian Peninsula, where this variant was thought not to contribute to viral diversity.