Multi-scale modelling of textile reinforced artificial tubular aortic heart valves

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• 作者：Deepanshu Sodhani ; Stefanie Reese ; Ricardo Moreira ; Stefan Jockenhoevel…
• 关键词：Textile reinforced composite ; Artificial heart valve ; Multi ; scale modelling ; Anisotropic elasticity ; Finite elements
• 刊名：Meccanica
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：52
• 期：3
• 页码：677-693
• 全文大小：
• 刊物类别：Physics and Astronomy
• 刊物主题：Classical Mechanics; Civil Engineering; Automotive Engineering; Mechanical Engineering;
• 出版者：Springer Netherlands
• ISSN：1572-9648
• 卷排序：52

文摘

Tissue engineered heart valves equivalent to the native aortic heart valves are in development as an alternative to available prostheses. To achieve sufficient mechanical stiffness for application in tissue engineered valves exposed to the systemic circulation, the tissue is reinforced by a textile scaffold. Mechanical testing of structurally different textiles used as reinforcement in tissue engineered heart valves is expensive and time-consuming. The current study seeks to predict the behaviour of textile reinforced artificial heart valves using a multi-scale modelling approach. The complex textile structure was divided into simplified models at different scales. Virtual experiments were conducted on each of these models and their response was fitted by appropriate isotropic and anisotropic hyperelastic material models. The textile response was then used in a macro heart valve model, which was subjected to dynamic cardiac loading. It was shown that the current modelling approach is in good agreement with the real valve behaviour.