Electroosmotic flow in polymer-coated slits: a joint experimental/simulation study

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• 作者：Michele Monteferrante (1)
  Simone Melchionna (2)
  Umberto Marini Bettolo Marconi (3)
  Marina Cretich (1)
  Marcella Chiari (1)
  Laura Sola (1)
  
  1. Consiglio Nazionale delle Ricerche ; Istituto di Chimica del Riconoscimento Molecolare (ICRM-CNR) ; Via Mario Bianco ; 20131 ; Milan ; Italy
  2. Dipartimento di Fisica ; Consiglio Nazionale delle Ricerche ; Istituto dei Processi Chimico-Fisici (IPCF-CNR) ; Universit脿 La Sapienza ; P.le A. Moro2 ; 00185 ; Rome ; Italy
  3. Scuola di Scienze e Tecnologie ; Universit脿 di Camerino and Istituto Nazionale di Fisica Nucleare (PG) ; Via Madonna delle Carceri ; 62032 ; Camerino ; Italy
  
• 刊名：Microfluidics and Nanofluidics
• 出版年：2015
• 出版时间：March 2015
• 年：2015
• 卷：18
• 期：3
• 页码：475-482
• 全文大小：674 KB
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• 刊物类别：Engineering
• 刊物主题：Engineering Fluid Dynamics
  Medical Microbiology
  Polymer Sciences
  Nanotechnology
  Mechanics, Fluids and Thermodynamics
  Engineering Thermodynamics and Transport Phenomena
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1613-4990

文摘

The quality of separation in capillaries electrophoresis is strongly affected by the magnitude of the electroosmotic flow (EOF). The EOF can be efficiently suppressed by coating the capillary wall with hydrophilic polymers. In this paper, experimental data are presented to show the effect of coating thickness and charge on mass transport. Simulations performed with the lattice Boltzmann technique quantitatively reproduce the EOF with and without the coating and with either a neutral or charged coating layer. Experimental, simulation and theoretical analyses converge toward the interpretation that EO suppression arises from the frictional forces acting on the ionic currents and that a detailed representation of the polymeric coating is not needed in order to capture the phenomenon.