Combatting resistance in intensive care: the multimodal approach of the Spanish ICU 鈥?em class="a-plus-plus">Zero Resistance鈥?program

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• 作者：Jos茅 Garnacho Montero (1)
  Francisco 脕lvarez Lerma (2)
  Paula Ram铆rez Galleymore (3)
  Mercedes Palomar Mart铆nez (4)
  Luis 脕lvarez Rocha (5)
  Fernando Barcenilla Gaite (4)
  Joaqu铆n 脕lvarez Rodr铆guez (6)
  Mercedes Catal谩n Gonz谩lez (7)
  Inmaculada Fern谩ndez Moreno (8)
  Jes煤s Rodr铆guez Ba帽o (9)
  Jos茅 Campos (10)
  Jes煤s Ma Aranaz Andr茅s (11)
  Yolanda Agra Varela (12)
  Carolina Rodr铆guez Gay (12)
  Miguel S谩nchez Garc铆a (13)
  The Scientific Expert Committee for the 鈥淶ero Resistance鈥?Project
  
  1. Hospital V铆rgen del Roc铆o ; Sevilla ; Spain
  2. Hospital del Mar ; Barcelona ; Spain
  3. Hospital La F茅 ; Valencia ; Spain
  4. Hospital Arnau de Vilanova ; L茅rida ; Spain
  5. Complejo Hospitalario La Coru帽a ; La Coru帽a ; Spain
  6. Hospital de Fuenlabrada ; Fuenlabrada ; Madrid ; Spain
  7. Hospital Doce de Octubre ; Madrid ; Spain
  8. Hospital Parc Taul铆 ; Sabadell ; Barcelona ; Spain
  9. Hospital V铆rgen Macarena ; Sevilla ; Spain
  10. Centro Nacional de Microbiolog铆a ; Majadahonda ; Madrid ; Spain
  11. Hospital Ram贸n y Cajal ; Madrid ; Spain
  12. Spanish Ministry of Health ; Madrid ; Spain
  13. Hospital Cl铆nico San Carlos ; Madrid ; Spain
  
• 刊名：Critical Care
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：19
• 期：1
• 全文大小：416 KB
• 参考文献：1. Boucher, HW, Talbot, GH, Bradley, JS (2009) Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America. Clin Infect Dis 48: pp. 1-12 CrossRef
  2. Antimicrobial resistance interactive database (EARS-Net). Available at: microbial_resistance/database/Pages/database.aspx" class="a-plus-plus">http://www.ecdc.europa.eu/en/healthtopics/antimicrobial_resistance/database/Pages/database.aspx (Accessed 4 September 2014).
  3. Jones, RN, Flonta, M, Gurler, N, Cepparulo, M, Mendes, RE, Castanheira, M (2014) Resistance surveillance program report for selected European nations (2011). Diagn Microbiol Infect Dis 78: pp. 429-36 microbio.2013.10.008" target="_blank" title="It opens in new window">CrossRef
  4. Cisneros, JM, Rodr铆guez-Ba帽o, J, Fern谩ndez-Cuenca, F (2005) Risk factors for the acquisition of imipenem-resistant Acinetobacter baumannii in Spain: A nationwide study. Clin Microbiol Infect 11: pp. 874-9 CrossRef
  5. Villar, M, Cano, ME, Gato, E (2014) Epidemiologic and clinical impact of Acinetobacter baumannii colonization and infection: A reappraisal. Medicine (Baltimore) 93: pp. 202-10 CrossRef
  6. Tacconelli, E, Cataldo, MA, Dancer, SJ (2014) European Society of Clinical Microbiology. ESCMID guidelines for the management of the infection control measures to reduce transmission of multidrug-resistant Gram-negative bacteria in hospitalized patients. Clin Microbiol Infect 20: pp. 1-55 CrossRef
  7. Estudio Nacional De Vigilancia De Infecci贸n Nosocomial En Servicios De Medicina Intensiva. Available at: me%20ENVIN-UCI%202013.pdf" class="a-plus-plus">http://hws.vhebron.net/envin-helics/Help/Informe%20ENVIN-UCI%202013.pdf. Accessed Oct 22, 2014.
  8. Siegel, JD, Rhinehart, E, Jackson, M, Chiarello, L (2007) Healthcare Infection Control Practices Advisory Committee. Management of multidrug-resistant organisms in health care settings, 2006. Am J Infect Control 35: pp. S165-93 CrossRef
  9. Neidell, MJ, Cohen, B, Furuya, Y (2012) Costs of healthcare- and community-associated infections with antimicrobial-resistant versus antimicrobial-susceptible organisms. Clin Infect Dis 55: pp. 807-15 CrossRef
  10. Garc铆a-Garmendia, JL, Ortiz-Leyba, C, Garnacho-Montero, J, Jim茅nez-Jim茅nez, FJ, Monterrubio-Villar, J, Gili-Miner, M (1999) Mortality and the increase in length of stay attributable to the acquisition of Acinetobacter in critically ill patients. Crit Care Med 27: pp. 1794-9 CrossRef
  11. Zhuo, H, Yang, K, Lynch, SV (2008) Increased mortality of ventilated patients with endotracheal Pseudomonas aeruginosa without clinical signs of infection. Crit Care Med 36: pp. 2495-503 CrossRef
  12. Palomar, M, 脕lvarez-Lerma, F, Riera, A (2013) Impact of a national multimodal intervention to prevent catheter-related bloodstream infection in the ICU: the Spanish experience. Crit Care Med 41: pp. 2364-72 CrossRef
  13. Alvarez Lerma, F, S谩nchez Garc铆a, M, Lorente, L (2014) Guidelines for the prevention of ventilator-associated pneumonia and their implementation. The Spanish 鈥淶ero-VAP鈥?bundle. Med Intensiva 38: pp. 226-36 medin.2013.12.007" target="_blank" title="It opens in new window">CrossRef
  14. Pronovost, P, Needham, D, Berenholtz, S (2006) An intervention to decrease catheter-related bloodstream infections in the ICU. N Engl J Med 355: pp. 2725-32 CrossRef
  15. Rello, J, Lode, H, Cornaglia, G, Masterton, R, Care Bundle Contributors, VAP (2010) A European care bundle for prevention of ventilator-associated pneumonia. Intensive Care Med 36: pp. 773-80 CrossRef
  16. Burke, JP (2003) Infection control 鈥?a problem for patient safety. N Engl J Med 348: pp. 651-6 CrossRef
  17. Pinder, M, Bellomo, R, Lipman, J (2002) Pharmacological principles of antibiotic prescription in the critically ill. Anaesth Intensive Care 30: pp. 134-44
  18. Thomas, JK, Forrest, A, Bhavnani, SM, Hyatt, JM, Cheng, A, Ballow, CH (1998) Pharmacodynamic evaluation of factors associated with the development of bacterial resistance in acutely ill patients during therapy. Antimicrob Agents Chemother 42: pp. 521-57
  19. Garnacho-Montero, J, Garcia-Garmendia, JL, Barrero-Almodovar, A, Jimenez-Jimenez, FJ, Perez-Paredes, C, Ortiz-Leyba, C (2003) Impact of adequate empirical antibiotic therapy on the outcome of patients admitted to the intensive care unit with sepsis. Crit Care Med 31: pp. 2742-51 CrossRef
  20. Heenen, S, Jacobs, F, Vincent, JL (2013) Antibiotic strategies in severe nosocomial sepsis: why do we not deescalate more often?. Crit Care Med 40: pp. 1404-9 CrossRef
  21. Garnacho-Montero, J, Guti茅rrez-Pizarraya, A, Escoresca-Ortega, A (2014) De-escalation of empirical therapy is associated with lower mortality in patients with severe sepsis and septic shock. Intensive Care Med 40: pp. 32-40 CrossRef
  22. Mokart, D, Slehofer, G, Lambert, J (2014) De-escalation of antimicrobial treatment in neutropenic patients with severe sepsis: results from an observational study. Intensive Care Med 40: pp. 41-9 CrossRef
  23. Pelletier, SJ, Crabtree, TD, Gleason, TG (1999) Waiting for microbiologic data to direct therapy against nosocomial infections in febrile surgical patients: are outcomes worsened?. Arch Surg 134: pp. 1300-7 CrossRef
  24. Hranjec, T, Rosenberger, LH, Swenson, B (2012) Aggressive versus conservative initiation of antimicrobial treatment in critically ill surgical patients with suspected intensive-care-unit-acquired infection: a quasi-experimental, before and after observational cohort study. Lancet Infect Dis 12: pp. 774-80 CrossRef
  25. Goeschel, CA, Bourgault, A, Palleschi, M (2006) Nursing lessons from the MHA keystone ICU project: developing and implementing an innovative approach to patient safety. Crit Care Nurs Clin North Am 18: pp. 481-92 CrossRef
  26. Vandijck, DM, Labeau, SO, Secanell, M, Rello, J, Blot, SI (2009) The role of nurses working in emergency and critical care environments in the prevention of intravascular catheter-related bloodstream infections. Int Emerg Nurs 17: pp. 60-8 CrossRef
  27. Rodr铆guez-Ba帽o, J, Bischofberger, C, 脕lvarez-Lerma, F (2008) Vigilancia y control de Staphylococcus aureus resistente a meticilina en hospitales espa帽oles. Documento de consenso GEIH-SEIMC y SEMPSPH. Enferm Infecc Microbiol Clin 26: pp. 285-98 CrossRef
  28. Sunenshine, RH, Liedtke, LA, Fridkin, SK, Strausbaugh, LJ (2005) Infectious Diseases Society of America Emerging Infections Network. Management of inpatients colonized or infected with antimicrobial-resistant bacteria in hospitals in the United States. Infect Control Hosp Epidemiol 26: pp. 138-43 CrossRef
  29. Mart铆nez Mart铆nez, Eliecer Cano M, Dom铆nguez MA et al. (2007) Cultivos de vigilancia epidemiol贸gica de bacterias resistentes a los antimicrobianos de inter茅s nosocomial En: E. Cercenado y R. Cant贸n. Procedimientos de Microbiolog铆a Cl铆nica. Recomendaciones de la Sociedad Espa帽ola de Enfermedades Infecciosas y Microbiolog铆a Cl铆nica (SEIMC). Available at. mc.org/documentos/protocolos/microbiologia" class="a-plus-plus">http://www.seimc.org/documentos/protocolos/microbiologia.
  30. L贸pez-Pueyo, MJ, Barcenilla-Gaite, F, Amaya-Villar, R, Garnacho-Montero, J (2011) Multirresistencia antibi贸tica en unidades de cr铆ticos. Med Intensiva 35: pp. 41-53 medin.2010.07.011" target="_blank" title="It opens in new window">CrossRef
  31. Nseir, S, Grailles, G, Soury-Lavergne, A, Minacori, F, Alves, I, Durocher, A (2010) Accuracy of American Thoracic Society/Infectious Diseases Society of America criteria in predicting infection or colonization with multidrug-resistant bacteria at intensive-care unit admission. Clin Microbiol Infect 16: pp. 902-8 CrossRef
  32. Nseir, S, Pompeo, C, Diarra, M (2007) Relationship between immunosuppression and intensive care unit-acquired multidrug-resistant bacteria: a case鈥揷ontrol study. Crit Care Med 35: pp. 1318-23 CrossRef
  33. McKinnell, JA, Miller, LG, Eells, SJ, Cui, E, Huang, SS (2013) A systematic literature review and meta-analysis of factors associated with methicillin-resistant Staphylococcus aureus colonization at time of hospital or intensive care unit admission. Infect Control Hosp Epidemiol 34: pp. 1077-86 CrossRef
  34. Boyce, JM, Pittet, D (2002) Guideline for Hand Hygiene in Health-Care Settings: recommendations of the Healthcare Infection Control Practices Advisory Committee and the HICPAC/SHEA/APIC/IDSA Hand Hygiene Task Force. Infect Control Hosp Epidemiol 23: pp. S3-40 CrossRef
  35. Siegel, JD, Rhinehart, E, Jackson, M, Chiarello, L (2007) Guideline for isolation precautions: Preventing transmission of infectious agents in health care settings. Am J Infect Control 35: pp. S65-164 CrossRef
  36. Larson, EL, Quiros, D, Lin, SX (2007) Dissemination of the CDC鈥檚 Hand Hygiene Guideline and impact on infection rates. Am J Infect Control 35: pp. 666-75 CrossRef
  37. Goodman, ER, Platt, R, Bass, R, Onderdonk, AB, Yokoe, DS, Huang, SS (2008) Impact of an environmental cleaning intervention on the presence of methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci on surfaces in intensive care unit rooms. Infect Control Hosp Epidemiol 29: pp. 593-9 CrossRef
  38. Carling, PC, Parry, MF, Bruno-Murtha, LA, Dick, B (2010) Improving environmental hygiene in 27 intensive care units to decrease multidrug-resistant bacterial transmission. Crit Care Med 38: pp. 1054-9 CrossRef
  39. Matlow, AG (2012) Attitudes and beliefs, not just knowledge, influence the effectiveness of environmental cleaning by environmental service workers. Am J Infect Control 40: pp. 260-2 CrossRef
  40. Wendt, C, Schinke, S, W眉rttemberger, M, Oberdorfer, K, Bock-Hensley, O, Baum, H (2007) Value of whole-body washing with chlorhexidine for the eradication of methicillin-resistant Staphylococcus aureus: a randomized, placebo-controlled, double-blind clinical trial. Infect Control Hosp Epidemiol 28: pp. 1036-43 CrossRef
  41. Borer, A, Gilad, J, Porat, N (2007) Impact of 4% chlorhexidine whole-body washing on multidrug-resistant Acinetobacter baumannii skin colonisation among patients in a medical intensive care unit. J Hosp Infect 67: pp. 149-55 CrossRef
  42. Popovich, KJ, Hota, B, Hayes, R, Weinstein, RA, Hayden, MK (2009) Effectiveness of routine patient cleansing with chlorhexidine gluconate for infection prevention in the medical intensive care unit. Infect Control Hosp Epidemiol 30: pp. 959-63 CrossRef
  43. Climo, MW, Sepkowitz, KA, Zuccotti, G (2009) The effect of daily bathing with chlorhexidine on the acquisition of methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus, and healthcare-associated bloodstream infections: results of a quasi-experimental multicenter trial. Crit Care Med 37: pp. 1858-65 CrossRef
  44. Derde, LP, Dautzenberg, MJ, Bonten, MJ (2012) Chlorhexidine body washing to control antimicrobial-resistant bacteria in intensive care units: a systematic review. Intensive Care Med 38: pp. 931-9 CrossRef
  45. Derde, LP, Cooper, BS, Goossens, H (2014) Interventions to reduce colonisation and transmission of antimicrobial-resistant bacteria in intensive care units: an interrupted time series study and cluster randomised trial. Lancet Infect Dis 14: pp. 31-9 CrossRef
  46. Climo, MW, Yokoe, DS, Warren, DK (2013) Effect of daily chlorhexidine bathing on hospital-acquired infection. N Engl J Med 368: pp. 533-42 CrossRef
  47. Singh, A, Goering, RV, Simjee, S, Foley, SL, Zervos, MJ (2006) Application of molecular techniques to the study of hospital infection. Clin Microbiol Rev 19: pp. 512-30 CrossRef
  48. Sabat, AJ, Budimir, A, Nashev, D (2013) Overview of molecular typing methods for outbreak detection and epidemiological surveillance. Euro Surveill 18: pp. 20380
  49. m-laboratorios.isciii.es/" class="a-plus-plus">https://cnm-laboratorios.isciii.es/.
  50. Hawe, CS, Ellis, KS, Cairns, CJ, Longmate, A (2009) Reduction of ventilator-associated pneumonia: active versus passive guideline implementation. Intensive Care Med 35: pp. 1180-6 CrossRef
  51. macion.sanidadmadrid.org/moodle/?lang=en" class="a-plus-plus">http://formacion.sanidadmadrid.org/moodle/?lang=en.
  52. http://hws.vhebron.net/envin-helics/.
  53. http://hws.vhebron.net/resistencia-zero/RZero.asp.
  
• 刊物主题：Intensive / Critical Care Medicine; Emergency Medicine;
• 出版者：BioMed Central
• ISSN：1364-8535

文摘

This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2015 and co-published as a series in Critical Care. Other articles in the series can be found online at http://ccforum.com/series/annualupdate2015. Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www.springer.com/series/8901.