Regulation of Postoperative Ileus by Lentivirus-Mediated HuR RNA Interference via the p38/MK2 Signaling Pathway

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• 作者：Ye Dao Xiong ; Lu Xing Rong ; Chi Pan
• 关键词：Postoperative ileus ; Inflammatory mechanisms ; Inflammatory cytokines ; HuR ; Lentivirus ; p38/MK2
• 刊名：Journal of Gastrointestinal Surgery
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：21
• 期：2
• 页码：389-397
• 全文大小：
• 刊物主题：Surgery; Gastroenterology;
• 出版者：Springer US
• ISSN：1873-4626
• 卷排序：21

文摘

ObjectivesThe objective of the present study is to explore the effect of lentivirus-mediated HuR interference on the development and progression of postoperative ileus and the role of HuR in the regulation of the p38/MAPK-activated protein kinase-2 (MK2) signaling pathway during postoperative ileus.