Motilit?tsst?rungen des ?sophagus
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  • 作者:PD Dr. E. Bruder (1)
    A.-L. Rougemont (2)
    R.I. Furlano (3)
    J.F. Schneider (3)
    J. Mayr (3)
    F.-M. Haecker (3)
    K. Beier (4)
    J. Schneider (5)
    P. Weber (3)
    T. Berberich (6)
    G. Cathomas (7)
    W.A. Meier-Ruge (1)
  • 关键词:?sophagus ; Motilit?tsst?rung ; Achalasie ; Enterisches Nervensystem ; Myopathie ; Esophagus ; Dysmotility ; Achalasia ; Enteric nervous system ; Myopathy
  • 刊名:Der Pathologe
  • 出版年:2013
  • 出版时间:March 2013
  • 年:2013
  • 卷:34
  • 期:2
  • 页码:118-132
  • 全文大小:1,900 KB
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  • 作者单位:PD Dr. E. Bruder (1)
    A.-L. Rougemont (2)
    R.I. Furlano (3)
    J.F. Schneider (3)
    J. Mayr (3)
    F.-M. Haecker (3)
    K. Beier (4)
    J. Schneider (5)
    P. Weber (3)
    T. Berberich (6)
    G. Cathomas (7)
    W.A. Meier-Ruge (1)

    1. Institut für Pathologie, Universit?tsspital Basel, Sch?nbeinstr. 40, 4031, Basel, Schweiz
    2. Division of Clinical Pathology, Geneva University Hospitals, Geneva, Schweiz
    3. Universit?ts-Kinderspital beider Basel, Basel, Schweiz
    4. Institut für Anatomie, Departement Biomedizin, Universit?t Basel, Basel, Schweiz
    5. Department of Pathology, Addis Ababa University, Addis Ababa, ?thiopien
    6. Abteilung für Kinderchirurgie, St. Elisabethen-Krankenhaus gGmbH L?rrach, L?rrach, Deutschland
    7. Institut für Pathologie, Kantonsspital Liestal, Liestal, Schweiz
  • ISSN:1432-1963
文摘
Motility disorders of the esophagus comprise a heterogeneous spectrum of diseases. Primary malformations of the esophagus are now amenable to improved surgical and gastroenterological therapies; however, they often lead to persistent long-term esophageal dysmotility. Achalasia originates from impaired relaxation of the gastroesophageal sphincter apparatus. Systemic diseases may give rise to secondary disorders of esophageal motility. A number of visceral neuromuscular disorders show an esophageal manifestation but aganglionosis rarely extends into the esophagus. The growing group of myopathies includes metabolic and mitochondrial disorders with increasing levels of genetic characterization and incipient emergence of therapeutic strategies. Esophagitis with an infectious etiology causes severe dysmotility particularly in immunocompromised patients. Immunologically mediated inflammatory processes involving the esophagus are increasingly better understood. Finally, rare tumors and tumor-like lesions may impair esophageal motor function.

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