Intêret du FibroScan® et des marqueurs biologiques de la fibrose hépatique, chez des sénégalais porteurs chroniques du virus de l'hépatite B faiblement réplicatifs

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• 作者：P. S. Touré ; M. M. Diop ; G. Lô ; A. Sow-Sall…
• 关键词：HBV infection ; Liver fibrosis ; Non invasive markers ; Thies
• 刊名：Journal Africain d'H¨¦pato-Gastroent¨¦rologie
• 出版年：2016
• 出版时间：March 2016
• 年：2016
• 卷：10
• 期：1
• 页码：14-20
• 全文大小：303 KB
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• 作者单位：P. S. Touré (1)
  M. M. Diop (1)
  G. Lô (2)
  A. Sow-Sall (2)
  J. A. Da Veiga (1)
  M. M. Sarr (1)
  A. Berthé (1)
  P. Dioussé (1)
  B. P. Ndiaye (2)
  C. T. Tall (3)
  B. M. Diop (1)
  N. C. Touré-Kane (2)
  M. M. Ka (1)
  S. Mboup (2)
  
  1. UFR des sciences de la Santé, Université de Thiès, Thiès, Sénégal
  2. Laboratoire de bactériologie-virologie, Hôpital Aristide Le Dantec de Dakar, Dakar, Sénégal
  3. Centre hospitalier national de Pikine Dakar, Dakar, Sénégal
  
• 刊物主题：Gastroenterology; Infectious Diseases; Tropical Medicine;
• 出版者：Springer Paris
• ISSN：1954-3212

文摘

Background and objectives Infection with Hepatitis B Virus (HBV) is the most common cause of acute and chronic liver desease all over the world. Patients with low viral load and normal transaminases have a lesser risk of progression to fibrosis.We evaluated the proportion of chronic HBV patients without cytolysis with a low viral replication, not responding to antiviral treatment criteria founded on international recommendations; but requiring treatment based of significant fibrosis at FibroScan®.