Acquired genetic alterations in tumor cells dictate the development of high-risk neuroblastoma and clinical outcomes
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- 作者：Faizan H. Khan ; Vijayabaskar Pandian ; Satishkumar Ramraj ; Mohan Natarajan…
- 关键词：High ; risk aggressive neuroblastoma ; Genetic rearrangements ; Karyotyping ; Array CGH ; Tumor progression ; Clinical outcomes
- 刊名：BMC Cancer
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：15
- 期：1
- 全文大小：3,451 KB
- 刊物主题：Cancer Research; Oncology; Stem Cells; Animal Models; Internal Medicine;
- 出版者：BioMed Central
- ISSN：1471-2407
文摘
Background Determining the driving factors and molecular flow-through that define the switch from favorable to aggressive high-risk disease is critical to the betterment of neuroblastoma cure.