Osteosarkommanifestation bei chronischer Osteomyelitis

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• 作者：Dr. C. Druschel (1)
  T. Pirvu (1)
  K.D. Schaser (1)
  P. Schwabe (1)
  I. Melcher (1)
  
• 关键词：Osteosarkome ; sekund盲re ; Maligne Entartung ; Umkippplastik ; Femur ; distaler ; Fibulatransposition ; Osteosarcoma ; secondary ; Secondary malignancy ; Rotation plasty ; Femur ; distal ; Fibula transposition
• 刊名：Der Unfallchirurg
• 出版年：2013
• 出版时间：September 2013
• 年：2013
• 卷：116
• 期：9
• 页码：854-859
• 全文大小：723KB
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• 作者单位：Dr. C. Druschel (1)
  T. Pirvu (1)
  K.D. Schaser (1)
  P. Schwabe (1)
  I. Melcher (1)
  
  1. Centrum f眉r Muskuloskelettale Chirurgie, Charit茅 鈥?Universit盲tsmedizin Berlin, Campus Virchow, Augustenburger Platz 1, 13353, Berlin, Deutschland
  
• ISSN：1433-044X

文摘

The treatment and outcome of two patients suffering from osteosarcoma of the lower extremity evolving many years after manifestation of chronic osteomyelitis are reported. After neoadjuvant polychemotherapy in one patient en bloc resection, interposition of a cement spacer and stabilization was performed in both cases. After eradication of infections final segmental reconstruction was accomplished by knee arthrodesis using rotation plasty of the split femoral condyle, free local fibula transposition and gastrocnemius muscle transfer. A custom-made diaphyseal replacement (3D-rapid prototyping titanium mesh) was used for defect reconstruction. After 1 year postoperative follow-up and restaging both patients showed no evidence of recurrent disease and had no local or systemic signs of infection.