Abnormal liver function in different patients with Schistosoma japonicum
详细信息 查看全文
- 作者：An Ning ; Xiaoying Wu ; Hongyu Li ; Jinyi Liang ; Zulu Gao ; Jia Shen…
- 关键词：Schistosomiasis japonica ; Liver function ; Abnormal
- 刊名：Parasitology Research
- 出版年：2015
- 出版时间：January 2015
- 年：2015
- 卷：114
- 期：1
- 页码：85-90
- 全文大小：136 KB
- 参考文献：1. Al-Hanafi N, Monem F (2014) Hepatitis B splice-generated protein antibodies in Syrian chronic hepatitis B patients: incidence and significance. Hepat Mon 14(4):e13166 CrossRef
2. Andrade ZA (2004) Schistosomal hepatopathy. Mem Inst Oswaldo Cruz 99(suppl I):51-7
3. Bogliolo L (1957) The anatomical picture of the liver in hepatosplenic schistosomiasis mansoni. Ann Trop Med Parasitol 51:1-4
4. Cai WM, Ma YL, Fu BZ (1985) Preliminary investigation on serum markers of hepatitis B virus in patients with schistosomiasis japonica. Chin Med J (Engl) 98(10):717-20
5. Cai WM, Tao J, Weng HL, Liu RH (2003) Study on the influence factors of the serum fibrosis markers. Chin J Hepatol 11(1):23-5
6. Chen MG (2014) Assessment of morbidity due to Schistosoma japonicum infection in China. Infect Dis Poverty 3(1):6 CrossRef
7. Chen X et al (2014) A description of the hepatitis B virus genomic background in a high-prevalence area in China. Virol J 11(1):101 CrossRef
8. Dang H et al (2014) Monitoring the transmission of Schistosoma japonicum in potential risk regions of China, 2008-012. Int J Environ Res Public Health 11(2):2278-287 CrossRef
9. El-Sabah AA, El-Metwally MT, Abozinadah NY (2011) Hepatitis C and B virus in schistosomiasis patients on oral or parenteral treatment. J Egypt Soc Parasitol 41(2):307-14
10. Goncalves EM, Campos R, Amato Neto V, Pinta PL, Moreira AA (1988) Use of sodium azide, as feces preservative, for the study of eggs of Schistosoma mansoni by the Kato-Katz method. Rev Soc Bras Med Trop 21(2):55-8 CrossRef
11. Kunika K, Itakura M, Yamashita K (1991) Correction of fructosamine value for serum albumin and globulin concentrations. Diabetes Res Clin Pract 13(1-):37-4 CrossRef
12. Li Y et al (1993) A study and analysis of the deaths due to advanced Schistosoma japonicum infection in the Dongting Lake area of China. J Trop Med Hyg 96(2):128-30
13. Pereira LM et al (1994) Hepatitis B virus infection in schistosomiasis mansoni. J Med Virol 42(2):203-06 CrossRef
14. Sato M et al (2014) Potential Associations between perihepatic lymph node enlargement and liver fibrosis, hepatocellular injury, or hepatocarcinogenesis in chronic hepatitis b virus infection. Hepatol res: the official journal of the Japan Society of Hepatology
15. St Symmers WC (1904) Note on a new form of liver cirrhosis due to the presence of the ova of Bilharzia haematobia. J Pathol Bacteriol 9:237-39 CrossRef
16. Tao J, Peng HQ, Cai WM, Dong FQ, Weng HL, Liu RH (2003) Influence factors of serum fibrosis markers in liver fibrosis. World J Gastroenterol 9(11):2497-500
17. Xiao L et al (2014) Parameters associated with significant liver histological changes in patients with chronic hepatitis B. ISRN Gastroenterol 2014:913890. doi:10.1155/2014/913890
18. Xie H, Chen D, Luo X, Gao Z, Fang H, Huang J (2013) Some characteristics of IL-5-producing T cells in mouse liver induced by Schistosoma japonicum infection. Parasitol Res 112(5):1945-951 CrossRef
19. Yan F, Zhao J, Ma J, Li Z, Su Q (2003) Metabolic effects of a novel bioartificial liver on serum from severe hepatitis patients: an in vitro study. Chin Med J (Engl) 116(10):1471-474 - 作者单位：An Ning (1)
Xiaoying Wu (2)
Hongyu Li (1)
Jinyi Liang (3) (4)
Zulu Gao (1)
Jia Shen (3) (4)
Zhen Liu (3) (4)
Jun Xu (1)
Fei Hu (1)
Feng Wu (3) (4)
Pengyu Ji (3) (4)
Zhongdao Wu (3) (4)
Xi Sun (3) (4)
1. Jiangxi Provincial Institute of Parasitic Diseases, Nanchang, China
2. Department of Biostatistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, China
3. Key Laboratory of Tropical Diseases and Control of the Ministry of Education, Guangzhou, China
4. Department of Parasitology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, People’s Republic of China - 刊物类别：Biomedical and Life Sciences
- 刊物主题：Biomedicine
Medical Microbiology
Microbiology
Immunology - 出版者：Springer Berlin / Heidelberg
- ISSN：1432-1955
文摘
Schistosomiasis japonica, caused by Schistosoma japonicum, is still a serious public health problem in China. It is important for schistosomiasis control to prevent from infection and advanced patients. Recent years, however, the form of the prevalence of schistosomiasis japonica in China was changed these days. Paying attention to the quality of life of these patients already infected with S. japonicum becomes a new objective to schistosomiasis control program. Although most of the chronic infections with S. japonicum will finally appear as liver fibrosis symptoms, it is still unknown liver function abnormalities in patients with severe forms of schistosomiasis, and there is also no evidence whether S. japonicum infection will directly cause damage to liver cells. Thus, this study investigated 494 patients diagnosed with S. japonicum (87.7?%) and 69 healthy subjects from a endemic areas belonging to Jiangxi Province of China and aimed to evaluate the liver function abnormalities in patients with severe forms of schistosomiasis and possible associations with coinfection with HBV. The results showed that the hepatic metabolism situation significantly changed in patients infected with S. japonicum; meanwhile, the abnormal rates of ALT and AST in patients with schistosomiasis were significantly higher than that in the control group, which confirmed that patients infected with S. japonicum not only had damaged liver function but also the hepatic cells were directly influenced. And the coinfection of CHB and schistosomiasis japonica can be a risk factor for more serious outcomes in patients from endemic areas. These results give us the advice that in the further treatment of patients infected with S. japonicum, especially these coinfections, we should better give the routine liver-protection treatment in advance.