Improvement in the docosahexaenoic acid production of Schizochytrium sp. S056 by replacement of sea salt

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• 作者：Wei Chen ; Pengpeng Zhou ; Yuanmin Zhu ; Chen Xie…
• 关键词：Marine microalgae ; Schizochytrium ; Docosahexaenoic acid ; Sea salt ; Sodium sulfate ; Osmolality
• 刊名：Bioprocess and Biosystems Engineering
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：39
• 期：2
• 页码：315-321
• 全文大小：444 KB
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• 作者单位：Wei Chen (1) (2) (3)
  Pengpeng Zhou (1) (2) (3)
  Yuanmin Zhu (1) (2) (3)
  Chen Xie (1) (2)
  Lin Ma (1) (2) (3)
  Xiaopeng Wang (1) (2) (3)
  Zhendong Bao (1)
  Longjiang Yu (1) (2) (3)
  
  1. Department of Biotechnology, Institute of Resource Biology and Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, No. 1037 Luoyu Road, Wuhan, 430074, China
  2. Key Laboratory of Molecular Biophysics, Ministry of Education, Wuhan, 430074, China
  3. Wuhan Institute of Biotechnology, Wuhan, China
  
• 刊物类别：Chemistry and Materials Science
• 刊物主题：Chemistry
  Biotechnology
  Industrial Chemistry and Chemical Engineering
  Industrial and Production Engineering
  Waste Management and Waste Technology
  Waste Water Technology, Water Pollution Control, Water Management and Aquatic Pollution
  Food Science
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1615-7605

文摘

Schizochytrium is a marine microalga that requires high concentrations of sea salt for growth, although problems arise with significant amounts of chloride ions in the culture medium, which corrodes the fermenters. In this work, we evaluated that cell growth and docosahexaenoic acid (DHA) production can be improved when using 1 % (w/v) sodium sulfate instead of 2 % (w/v) sea salt in the culture medium for Schizochytrium sp. S056. In practice, the use of sodium sulfate as the sodium salt led to chloride ion levels in the medium that can be completely removed, thus avoiding fermenter corrosion during Schizochytrium sp. S056 growth, reducing cost and increasing DHA production, and simplifying the disposal of fermentation wastewater. Additionally, we demonstrated that the osmolality of growth media did not play a crucial role in the production of DHA. These findings may be significantly important to companies involved in production of PUFAs by marine microbes. Keywords Marine microalgae Schizochytrium Docosahexaenoic acid Sea salt Sodium sulfate Osmolality