Benzodiazepines and heightened aggressive behavior in rats: reduction by GABA A/a 1 receptor antagonists

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• 作者：Shannon L. Gourley ; Joseph F. DeBold ; Wenyuan Yin ; James Cook and Klaus A. Miczek
• 关键词：Aggression ; Benzodiazepines ; GABAA receptor ; GABA ; Motor activity ; Anxiolytics
• 刊名：Psychopharmacology
• 出版年：2005
• 出版时间：March 2005
• 年：2005
• 卷：178
• 期：2-3
• 页码：232-240
• 全文大小：244 KB
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Biomedicine
  Pharmacology and Toxicology
  Psychiatry
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1432-2072

文摘

Rationale Positive modulators of the benzodiazepine/GABA_A receptor complex can heighten aggressive behavior; the GABA_A/₁ subunit may play a critical role in benzodiazepine-modulated aggressive behavior.