Primary synovial sarcoma of pericardium: A case report

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• 作者：Rangreze Imran (1)
  Banday Manzoor Ahmad (1)
  Sheikh Aejaz Aziz (1)
  Bhat Salma (2)
  Mohammad Latif Charoo (3)
  
• 关键词：synovial sarcoma ; pericardium ; MRI
• 刊名：The Chinese-German Journal of Clinical Oncology
• 出版年：2011
• 出版时间：July 2011
• 年：2011
• 卷：10
• 期：7
• 页码：428-429
• 全文大小：216KB
• 参考文献：1. Moorjani N, Peebles C, Gallagher P, / et al. Pericardial Synovial Sarcoma. J Card Surg, 2009, 24: 349鈥?51. CrossRef
  2. Warren W, Malignancies involving the pericardium. Semin Thorac Cardiol Surg, 2000, 12: 119.
  3. Luna A, Ribes R, Caro P, / et al. Evaluation of cardiac tumors with MRI. Euro Radiol, 2005, 15: 1446鈥?455. CrossRef
  4. Ladanyi M, Antonescu CR, Leung DH, / et al. Impact of SYT-SSX fusion type on the clinical behavior of synovial sarcoma: a multi-institutional retrospective study of 243 patients. Cancer Res, 2002, 62: 135鈥?40.
  5. Patel SR, Vadhan -Rajs, Burges MA, / et al. Results of two consecutive trials of dose intensive chemotherapy with doxorubicin and ifosfamide in patients with sarcomas. Am J Clin Oncol, 1998, 21: 317. CrossRef
  6. Borden EC, Baker LH, Bell RS, / et al. Soft tissue sarcoma of adults: state of translational science. Clin Cancer Res, 2003, 9: 1941鈥?956.
  7. Gowdamarajan A, Michler RE. Therapy for primary cardiac tumour: is there any role for heart transplantation? Curr Opin Cardiol, 2000, 15: 121鈥?25. CrossRef
  8. Zhengrong W. Yun Z, Fuchun Z. Primary malignant pericardial sarcoma. Int J Cardiol, 2009, 136: 96鈥?9. CrossRef
  
• 作者单位：Rangreze Imran (1)
  Banday Manzoor Ahmad (1)
  Sheikh Aejaz Aziz (1)
  Bhat Salma (2)
  Mohammad Latif Charoo (3)
  
  1. Department of Medical Oncology, SKIMS, Srinagar, India
  2. Department of Pathology, SKIMS, Srinagar, India
  3. HIV Centre, SKIMS, Srinagar, India
  

文摘

Primary pericardial sarcomas are extremely rare. We report a case of 19 year old male who presented with cough, dyspnoea, and orthopnea. Investigations and exploratory thoracotomy revealed a large pericardial mass. Surgical debulking of the tumor was performed and the histopathological examination was compatible with synovial sarcoma. The tumor was unresectable due to its invasion and adhesion to mediastinal structures. Hence patient was started on palliative chemotherapy (adriamycin and ifosfamide based). Patient showed an initial symptomatic response but later on there was a clinical progression and died within six months of his diagnosis.