Basigin-2 upregulated by receptor activator of NF-κB ligand enhances lung cancer-induced osteolytic lesions
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- 作者：Cheng-Gong Liao ; Li Yao ; Wei Xie ; Lili Liu ; Sheng-Da Wu…
- 关键词：Basigin ; 2 ; Lung cancer ; Bone metastasis ; Osteolytic lesion ; RANKL
- 刊名：Cancer Cell International
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：16
- 期：1
- 全文大小：5,716 KB
- 刊物主题：Cancer Research; Cell Biology;
- 出版者：BioMed Central
- ISSN：1475-2867
文摘
Background Lung cancer bone metastasis causes poor prognosis. Basigin-2, a novel cancer-associated biomarker, is upregulated in lung cancer and has been linked with tumor progression. But little is known about the role of basigin-2 in lung cancer bone metastasis and osteolytic lesion.