The Resistance Analysis of Ureaplasma urealyticum and Mycoplasma hominis in Female Reproductive Tract Specimens

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• 作者：Guangyong Ye (1)
  Zhou Jiang (1)
  Min Wang (1)
  Jiamin Huang (1)
  Guochen Jin (1)
  Shiming Lu (1)
  
• 关键词：Ureaplasma urealyticum ; Mycoplasma hominis ; Drug resistance ; Infection
• 刊名：Cell Biochemistry and Biophysics
• 出版年：2014
• 出版时间：January 2014
• 年：2014
• 卷：68
• 期：1
• 页码：207-210
• 全文大小：198 KB
• 作者单位：Guangyong Ye (1)
  Zhou Jiang (1)
  Min Wang (1)
  Jiamin Huang (1)
  Guochen Jin (1)
  Shiming Lu (1)
  
  1. Women’s Reproductive Health Key Laboratory of Zhejiang Province, Women’s Hospital, School of Medicine, Zhejiang University, Xueshi Road 1#, Hangzhou, 310006, Zhejiang, China
  
• ISSN：1559-0283

文摘

The aim of this study was to analyze the drug resistance of Ureaplasma urealyticum (Uu) and Mycoplasma hominis (Mh) in female reproductive track from 2007 to 2011 in Hangzhou. Antibiotics sensitivity test in Mycoplasma, which was isolated in clinics from 2007 to 2011 were analyzed retrospectively. The detection of Mycoplasma during 2007-011 was 20,146 (54.37?%), of which the single infection rate of Uu was 42.08?%, of Mh 1.26?%, and of Uu+Mh was 11.02?%. The drug resistance rate?of Uu was increased significantly in ofloxacin in 2007 (41.80?%), 2008 (45.94?%), 2009 (46.07?%), 2010 (50.36?%), and 2011 (53.22?%) (P?<?0.05). The resistance rate to ciprofloxacin was significantly increased in 2007 (67.15?%), 2008 (67.44?%), 2009 (73.00?%), 2010 (75.28?%), and 2011 (75.28?%) (P?<?0.05). Exceptionally, the resistance rates of the other antibiotics were low. The drug resistance rate of Uu was significantly increased with quinolones at increasing tendency. It is necessary to monitor the local drug resistance rate of Uu regularly to provide reasonable guidelines in clinics.