Power spectrum and blood flow velocity images obtained by dual-beam backscatter laser Doppler velocimetry

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• 作者：Hiroki Ishida (1)
  Youichi Yasue (2)
  Tadashi Hachiga (1)
  Tsugunobu Andoh (3)
  Shunsuke Akiguchi (1)
  Yasushi Kuraishi (3)
  Tadamichi Shimizu (3)
  
• 关键词：laser Doppler velocimeter ; in ; vivo measurements ; blood flow ; microvessels
• 刊名：Optical Review
• 出版年：2014
• 出版时间：July 2014
• 年：2014
• 卷：21
• 期：4
• 页码：461-467
• 全文大小：1,681 KB
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• 作者单位：Hiroki Ishida (1)
  Youichi Yasue (2)
  Tadashi Hachiga (1)
  Tsugunobu Andoh (3)
  Shunsuke Akiguchi (1)
  Yasushi Kuraishi (3)
  Tadamichi Shimizu (3)
  
  1. Toyama National College of Technology, Imizu, Toyama, 933-0293, Japan
  2. Nippon Marine Enterprises Ltd., Yokosuka, Kanagawa, 238-0004, Japan
  3. Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, 930-0194, Japan
  
• ISSN：1349-9432

文摘

We developed a micro multipoint laser Doppler velocimeter (μ-MLDV) for noninvasive in-vivo measurements of blood flow and we presented the results of demonstrations performed on experimental animals. In this paper, we investigate the validity of power spectrum analysis for determining the flow velocity and the minimum power of the semiconductor laser in the μ-MLDV. Although average velocity is generally estimated from a peak position (f peak) in the power spectrum, the power spectrum of blood flow included an additional component in the high-frequency region. The conventional method for determining the average velocity of flows of transparent artificial fluids, which involves determining the average velocity from f peak, is unsuitable for in-vivo measurements of blood flow. The laser power was reduced from 140 to 30mW since 30mW was the minimum power at which images of blood flow velocity in microvessels could be obtained. About 30mW (power density of 15mW/mm2) is the maximum power which can be irradiated to humans. Further reduction in the laser power is necessary before this technique can be applied to humans.