Suppression of pancreatic beta cell apoptosis by Danzhi Jiangtang capsule contributes to the attenuation of type 1 diabetes in rats

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• 作者：Shuguo Zheng ; Mengqiu Zhao ; Yuanjie Wu…
• 关键词：Danzhi Jiangtang capsule ; Diabetes ; Pancreatic beta cells ; Apoptosis ; Pancreatic duodenal homeobox ; 1
• 刊名：BMC Complementary and Alternative Medicine
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：16
• 期：1
• 全文大小：3,687 KB
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• 作者单位：Shuguo Zheng (1)
  Mengqiu Zhao (1)
  Yuanjie Wu (2)
  Zheng Wang (3)
  Younan Ren (1)
  
  1. Department of Pharmacology, Wannan Medical College, Wuhu, 241002, China
  2. Department of Basic Theory of Chinese Medicine, Anhui University of Chinese Medicine, Hefei, 230038, China
  3. Department of Orthopedics and Traumatology, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, 230038, China
  
• 刊物主题：Complementary & Alternative Medicine; Internal Medicine; Chiropractic Medicine;
• 出版者：BioMed Central
• ISSN：1472-6882

文摘

Background Danzhi Jiangtang Capsule (DJC), a Chinese medicinal formula, has been clinically used for treatment of diabetes for many years. Previous studies have demonstrated that DJC was able to improve pancreatic islet function in diabetes, but the underlying mechanisms remained unclear.