Intertumor heterogeneity in vascularity and invasiveness of artificial melanoma brain metastases
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- 作者：Trude G. Simonsen ; Jon-Vidar Gaustad…
- 关键词：Melanoma ; Brain metastasis ; Angiogenesis ; Vascular co ; option ; Invasiveness
- 刊名：Journal of Experimental & Clinical Cancer Research
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：34
- 期：1
- 全文大小：3,692 KB
- 刊物主题：Oncology; Cancer Research;
- 出版者：BioMed Central
- ISSN：1756-9966
文摘
Background Patients diagnosed with melanoma brain metastases have few treatment options and poor prognosis, and improved treatment strategies for these patients require detailed understanding of the underlying pathobiology. In this investigation we studied the vascularity and invasiveness of artificial brain metastases established from four human melanoma cell lines.