Current understanding of the pathophysiological mechanisms responsible for inappropriate sinus tachycardia: role of the If “funny” current

详细信息    查看全文

• 作者：Mirko Baruscotti ; Elisabetta Bianco…
• 刊名：Journal of Interventional Cardiac Electrophysiology
• 出版年：2016
• 出版时间：June 2016
• 年：2016
• 卷：46
• 期：1
• 页码：19-28
• 全文大小：794 KB
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Cardiology
  
• 出版者：Springer Netherlands
• ISSN：1572-8595
• 卷排序：46

文摘

BackgroundTogether with the afferent branches of the autonomic nervous system, the sinoatrial node (SAN) forms a functional unit whose function is to fire rhythmic action potentials at a rate optimal for coping with the metabolic needs of the body. Dysfunctional behavior of this complex unit may thus result in SAN rhythm disorders. Among these disorders, there is the inappropriate sinus tachycardia (IST) which occurs when an unjustified fast SAN rate is present.