Performance of loop-mediated isothermal amplification (LAMP) for the diagnosis of malaria among malaria suspected pregnant women in Northwest Ethiopia
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- 作者：Banchamlak Tegegne ; Sisay Getie ; Wossenseged Lemma ; Abu Naser Mohon…
- 关键词：Malaria ; Diagnostics ; Pregnancy ; Molecular ; RDT
- 刊名：Malaria Journal
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：16
- 期：1
- 全文大小：946KB
- 刊物主题：Parasitology; Tropical Medicine; Infectious Diseases; Entomology; Microbiology; Public Health;
- 出版者：BioMed Central
- ISSN：1475-2875
- 卷排序：16
文摘
BackgroundMalaria is a major public health problem and an important cause of maternal and infant morbidity in sub-Saharan Africa, including Ethiopia. Early and accurate diagnosis of malaria with effective treatment is the best strategy for prevention and control of complications during pregnancy and infant morbidity and mortality. However, laboratory diagnosis has relied on the identification of malaria parasites and parasite antigens in peripheral blood using Giemsa-stained microscopy or rapid diagnostic tests (RDTs) which lack analytical and clinical sensitivity. The aim of this study was to evaluate the performance of loop-mediated isothermal amplification (LAMP) for the diagnosis of malaria among malaria suspected pregnant women in Northwest Ethiopia.