Diagnostic performance of shear wave elastography in the identification of malignant thyroid nodules: a meta-analysis

详细信息    查看全文

• 作者：Peiliang Lin ; Minqi Chen ; Baoxian Liu ; Siwen Wang ; Xiaoxi Li
• 关键词：Ult rasound ; Elasticity imaging techniques ; Thyroid neoplasms ; Thyroid nodule ; Meta ; analysis
• 刊名：European Radiology
• 出版年：2014
• 出版时间：November 2014
• 年：2014
• 卷：24
• 期：11
• 页码：2729-2738
• 全文大小：606 KB
• 参考文献：1. Tunbridge WMG, Evered DC, Hall R et al (1977) The spectrum of thyroid disease in a community: the Whickham survey. Clin Endocrinol 7:481-93 CrossRef
  2. Knudsen N, Laurberg P, Perrild H, Bülow I, Ovesen L, J?rgensen T (2002) Risk factors for goiter and thyroid nodules. Thyroid 12:879-88 CrossRef
  3. Reiners C, Wegscheider K, Schicha H et al (2004) Prevalence of thyroid disorders in the working population of Germany: ultrasonography screening in 96,278 unselected employees. Thyroid 14:926-32 CrossRef
  4. Singer PA, Cooper DS, Daniels GH et al (1996) Treatment guidelines for patients with thyroid nodules and well-differentiated thyroid cancer. American Thyroid Association. Arch Intern Med 156:2165-172 CrossRef
  5. Alexander EK (2008) Approach to the patient with a cytologically indeterminate thyroid nodule. J Clin Endocrinol Metab 93:4175-182 CrossRef
  6. Wojcinski S, Farrokh A, Weber S et al (2010) Multicenter study of ultrasound real-time tissue elastography in 779 cases for the assessment of breast lesions: improved diagnostic performance by combining the BI-RADS(R)-US classification system with sonoelastography. Ultraschall Med 31:484-91 CrossRef
  7. Aigner F, Mitterberger M, Rehder P et al (2010) Status of transrectal ultrasound imaging of the prostate. J Endourol 24:685-91 CrossRef
  8. Ying L, Lin X, Xie ZL, Tang FY, Hu YP, Shi KQ (2012) Clinical utility of acoustic radiation force impulse imaging for identification of malignant liver lesions: a meta-analysis. Eur Radiol 22:2798-805 CrossRef
  9. Bojunga J, Herrmann E, Meyer G, Weber S, Zeuzem S, Friedrich-Rust M Real-time elastography for the differentiation of benign and malignant thyroid nodules: a meta-analysis. Thyroid 20:1145-150
  10. Razavi SA, Hadduck TA, Sadigh G, Dwamena BA (2013) Comparative effectiveness of elastographic and B-mode ultrasound criteria for diagnostic discrimination of thyroid nodules: a meta-analysis. AJR Am J Roentgenol 200:1317 CrossRef
  11. Bamber J, Cosgrove D, Dietrich CF et al (2013) EFSUMB guidelines and recommendations on the clinical use of ultrasound elastography. Part 1: Basic principles and technology. Ultraschall Med 34:169-84 CrossRef
  12. Friedrich-Rust M, Romenski O, Meyer G et al (2012) Acoustic Radiation Force Impulse-Imaging for the evaluation of the thyroid gland: A limited patient feasibility study. Ultrasonics 52:69-4 CrossRef
  13. Gu J, Du L, Bai M et al (2012) Preliminary Study on the Diagnostic Value of Acoustic Radiation Force Impulse Technology for Differentiating Between Benign and Malignant Thyroid Nodules. J Ultrasound Med 31:763-71
  14. Sebag F, Vaillant-Lombard J, Berbis J et al (2010) Shear wave elastography: a new ultrasound imaging mode for the differential diagnosis of benign and malignant thyroid nodules. J Clin Endocrinol Metab 95:5281-288 CrossRef
  15. Yu L, Wu J, Li J (2012) Application Value of Virtual Touch Tissue Quantification in the Diagnosis of Papillary Thyroid Microcarcinoma. Chinese General Practice 15:3206-208
  16. Zhang FJ, Han RL (2013) The value of acoustic radiation force impulse (ARFI) in the differential diagnosis of thyroid nodules. Eur J Radiol 82:e686–e690 CrossRef
  17. Bhatia KS, Tong CS, Cho CC, Yuen EH, Lee YY, Ahuja AT (2012) Shear wave elastography of thyroid nodules in routine clinical practice: preliminary observations and utility for detecting malignancy. Eur Radiol 22:2397-406 CrossRef
  18. Xiao L, Zhao Y, Gao L et al (2012) Value of virtual touch tissue quantification technique in the diagnosis of small solid thyroid nodules. Chinese Journal of Ultrasonography 21:771-74
  19. Zhang F, Han R, Liu M (2012) Ultrasonic Elastography and Virtual Touch Tissue Quantification in Benign and Malignant Thyroid Nodules. Chinese Journal of Ultrasonic in Medicine 28:120-23
  20. Whiting P, Rutjes AW, Reitsma JB, Bossuyt PM, Kleijnen J (2003) The development of QUADAS: a tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews. BMC Med Res Methodol 3:25 CrossRef
  21. Met R, Bipat S, Legemate DA, Reekers JA, Koelemay MJ (2009) Diagnostic performance of computed tomography angiography in peripheral arterial disease: a systematic review and meta-analysis. JAMA 301:415-24 CrossRef
  22. van Houwelingen HC, Arends LR, Stijnen T (2002) Advanced methods in meta-analysis: multivariate approach and meta-regression. Stat Med 21:589-24 CrossRef
  23. van Houwelingen HC, Zwinderman KH, Stijnen T (1993) A bivariate approach to meta-analysis. Stat Med 12:2273-284 CrossRef
  24. Cooper DS, Doherty GM, Haugen BR et al (2006) Management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid 16:109-42 CrossRef
  25. Higgins JP, Thompson SG, Deeks JJ, Altman DG (2003) Measuring inconsistency in meta-analyses. BMJ 327:557-60 CrossRef
  26. Deeks JJ, Macaskill P, Irwig L (2005) The performance of tests of publication bias and other sample size effects in systematic reviews of diagnostic test accuracy was assessed. J Clin Epidemiol 58:882-93 CrossRef
  27. Bojunga J, Dauth N, Berner C et al (2012) Acoustic Radiation Force Impulse Imaging for Differentiation of Thyroid Nodules. PLoS One 7:e42735 CrossRef
  28. Chen S, Zhu L, Chen X et al (2011) Virtual touch tissue quantification in diagnosis of thyroid papillary carcinoma. Chin J Med Imaging Technol 27:2451-455
  29. Hou XJ, Sun AX, Zhou XL et al (2013) The application of Virtual Touch tissue quantification (VTQ) in diagnosis of thyroid lesions: A preliminary study. Eur J Radiol 82:797-01 CrossRef
  30. Ni J, Huang P, Zhang H et al (2013) Diagnostic value of virtual touch tissue quantification in discriminating thyroid benign and malignant nodule. Chin J Ultrasonogr 22:137-40
  31. Veyrieres JB, Albarel F, Lombard JV et al (2012) A threshold value in Shear Wave elastography to rule out malignant thyroid nodules: a reality? Eur J Radiol 81:3965-972 CrossRef
  32. Zhan J, Zhu L, Zhu J, Chai Q, Chen L, Chen Y (2012) Ultrasound elastography compared with acoustic radiation force impulse imagine in differential diagnosis of benign and malignant thyroid nodules. Chin J Med Imaging Technol 28:1815-818
  33. Zhang YF, Xu HX, He Y et al (2012) Virtual Touch Tissue Quantification of Acoustic Radiation Force Impulse: A New Ultrasound Elastic Imaging in the Diagnosis of Thyroid Nodules. PLoS One 7:e49094 CrossRef
  34. Kim JK, Baek JH, Lee JH et al (2009) Ultrasound elastography for thyroid nodules: a reliable study? Ultrasound Med Biol 38:1508-513 CrossRef
  35. Lim DJ, Luo S, Kim MH, Ko SH, Kim Y (2012) Interobserver agreement and intraobserver reproducibility in thyroid ultrasound elastography. Am J Roentgenol 198:896-01 CrossRef
  36. Melodelima D, Bamber JC, Duck FA, Shipley JA (2007) Transient elastography using impulsive ultrasound radiation force: a preliminary comparison with surface palpation elastography. Ultrasound Med Biol 33:959-69 CrossRef
  
• 作者单位：Peiliang Lin (1)
  Minqi Chen (2)
  Baoxian Liu (2)
  Siwen Wang (1)
  Xiaoxi Li (1)
  
  1. Department of Vascular and Thyroid Surgery, First Affiliated Hospital, Sun Yat-Sen University, 58 Zhongshan 2nd Road, Guangzhou, Guangdong, 510080, China
  2. Department of Ultrasound, First Affiliated Hospital, Sun Yat-Sen University, 58 Zhongshan 2nd Road, Guangzhou, Guangdong, 510080, China
  
• ISSN：1432-1084

文摘

Objective This meta-analysis aimed to assess the performance of shear wave elastography (SWE) in the identification of malignant thyroid nodules. Methods Web of Science, Scopus, PubMed, and the references of narrative reviews were searched for relevant studies with a publication date through October 2013. The methodological quality was assessed using QUADAS tools. Data synthesis was calculated using the bivariate mixed-effects regression model. Results Of the 131 studies identified, 15 (11.5?%) were included, in which SWE, point-SWE or 2D SWE, was used to evaluate 1,867 thyroid nodules in 1,525 patients. Methodological assessment revealed study quality was moderate to high. The pooled sensitivity, specificity, and area under the summary receiver operating characteristic curve of SWE for detecting malignant thyroid nodules were 84.3?% (95?% confidence interval [CI], 76.9-9.7?%), 88.4?% (95?% CI, 84.0-1.7?%), and 93?% (95?% CI, 90-5?%), respectively. As a screening tool, positive and negative predictive values were 27.7-4.7?% and 98.1-9.1?%, respectively, calculated with a malignance prevalence of 5-0?% in thyroid nodules. A publication bias regression test revealed no significant small-study bias. Conclusions SWE is a highly accurate diagnostic modality for the identification of malignant thyroid nodules, with promise for integration into routine imaging protocols for thyroid nodules. Key Points -Shear wave elastography (SWE) is a group of novel ultrasound-based technologies. -Meta-analysis was employed to assess relevant studies of SWE of thyroid nodules. -SWE had high sensitivity and specificity in identifying malignant thyroid nodules. -The high negative predictive value of SWE can reduce unnecessary biopsies.