Spatiotemporal changes of optical signals in the somatosensory cortex of neuropathic rats after electroacupuncture stimulation
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- 作者：Myeounghoon Cha ; Younbyoung Chae…
- 关键词：Electroacupuncture (EA) ; Neuropathic pain ; Primary somatosensory cortex (S1) ; Optical signal ; Spatiotemporal change
- 刊名：BMC Complementary and Alternative Medicine
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：17
- 期：1
- 全文大小：3472KB
- 刊物主题：Complementary & Alternative Medicine; Internal Medicine; Chiropractic Medicine;
- 出版者：BioMed Central
- ISSN：1472-6882
- 卷排序：17
文摘
BackgroundPeripheral nerve injury causes physiological changes in primary afferent neurons. Neuropathic pain associated with peripheral nerve injuries may reflect changes in the excitability of the nervous system, including the spinothalamic tract. Current alternative medical research indicates that acupuncture stimulation has analgesic effects in various pain symptoms. However, activation changes in the somatosensory cortex of the brain by acupuncture stimulation remain poorly understood. The present study was conducted to monitor the changes in cortical excitability, using optical imaging with voltage-sensitive dye (VSD) in neuropathic rats after electroacupuncture (EA) stimulation.