Subcutaneous Phaeohyphomycosis Caused by Pyrenochaeta romeroi in a Rheumatoid Arthritis Patient: A Case Report with Review of the Literature
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- 作者：Sonam Sharma ; Malini R. Capoor ; Mukul Singh ; Deepti Kiran…
- 关键词：Phaeohyphomycosis ; Subcutaneous ; Rheumatoid arthritis ; Pyrenochaeta romeroi
- 刊名：Mycopathologia
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：181
- 期：9-10
- 页码：735-743
- 全文大小：1,016 KB
- 刊物类别：Biomedical and Life Sciences
- 刊物主题：Life Sciences
Microbiology
Medical Microbiology
Plant Sciences
Microbial Ecology - 出版者：Springer Netherlands
- ISSN：1573-0832
- 卷排序：181
文摘
Pyrenochaeta romeroi is a rare fungal agent of chronic, suppurative subcutaneous infections leading to mycetoma. It is an unusual cause of deep, non-mycetomatous infections. We herein present review of the literature along with a case of 61-year-old Indian female with rheumatoid arthritis who developed subcutaneous phaeohyphomycosis caused by Pyrenochaeta romeroi. It posed a diagnostic challenge, as the culture from fine-needle aspirate revealed a non-sporulating dematiaceous mould, which was the only supportive tool for its diagnosis and initiation of the therapy. However, it was the molecular sequencing which played the pivotal role in clinching the final aetiological diagnosis. To the best of our knowledge, this is the 20th case of Pyrenochaeta species infection occurring worldwide and first case report of subcutaneous phaeohyphomycosis caused by Pyrenochaeta romeroi in a rheumatoid arthritis patient.