Anti-hyperglycemic and hypolipidemic effects of baechukimchi with Ecklonia cava in type 2 diabetic db/db mice
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- 作者：Hyun-Ah Lee ; Mi-hwa Park ; Yeong-Ok Song ; Mi-Soon Jang…
- 关键词：Ecklonia cava ; baechukimchi ; C57BLKS/J ; db/db mice ; antihyperglycemia ; hypolipidemia
- 刊名：Food Science and Biotechnology
- 出版年：2015
- 出版时间：February 2015
- 年：2015
- 卷：24
- 期：1
- 页码：307-314
- 全文大小：227 KB
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- 刊物主题：Chemistry
Nutrition
Food Science - 出版者：The Korean Society of Food Science and Technology in co-publication with Springer
- ISSN：2092-6456
文摘
Anti-hyperglycemic and hypolipidemic effects of baechukimchi with Ecklonia cava were investigated in type 2 diabetic db/db mice. Baechukimchi with 15% added E. cava (BKE) was fermented at 5°C for 28 days to obtain optimally ripened BKE (pH 4.28, acidity 0.71). BKE was subjected to extraction using 80% methanol. Male db/db mice were divided into groups of db/db-control, db/db-BKE, and db/db-rosiglitazone (db/db-RG). Compounds were orally administered every day for 6 weeks. The db/db-BKE mice had lowered blood glucose and plasma insulin levels. Plasma total cholesterol, triglyceride, and LDL-cholesterol levels in db/db-BKE mice were significantly (pdb/db mice, while db/db-BKE mice had significantly (pdb/db-BKE mice had significantly (pppdb/db-BKE mice than in db/db mice.