Bioactive compounds of sea cucumbers and their therapeutic effects

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• 作者：Shujuan Shi 时淑娟 ; Wenjing Feng 冯文静…
• 刊名：Chinese Journal of Oceanology and Limnology
• 出版年：2016
• 出版时间：May 2016
• 年：2016
• 卷：34
• 期：3
• 页码：549-558
• 全文大小：239 KB
• 刊物主题：Oceanography;
• 出版者：Springer Berlin Heidelberg
• ISSN：1993-5005
• 卷排序：34

文摘

Sea cucumbers belong to the Class Holothuroidea of marine invertebrates. They are commercially valuable and prized as a food and folk medicine in Asia. Nutritionally, sea cucumbers have an impressive profile of valuable nutrients such as vitamins, minerals and amino acids. A number of unique biological and pharmacological activities/properties, including anticancer, anticoagulant/antithrombotic, antimicrobial, antioxidant, antihyperlipidemic, antihyperglycemic, anti-inflammatory, antihypertension and radioprotective, have been ascribed to various compounds isolated from sea cucumbers. The therapeutic properties and medicinal benefits of sea cucumbers can be linked to the presence of a wide array of bioactives, especially triterpene glycosides, acid mucopolysaccharide, sphingoid bases, glycolipids, fucosylated chondroitin sulfate, polysaccharides, phospholipids, cerebrosides, phosphatidylcholines, and other extracts and hydrolysates. This review highlights the valuable bioactive components as well as the multiple therapeutic properties of sea cucumbers with a view to exploring their potential uses as functional foods and a natural source of new multifunctional drugs.Keywordssea cucumberbioactive compoundsbiological activitiespharmacological activitiestherapeutic effects