Relation between bone density and certain parameters of lipid status in postmenopausal women

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• 作者：Aleksandar Dimic (1)
  Marina Ra?ic Popovic (2)
  Ivan Tasic (1)
  Dragan Djordjevic (1)
  Sonja Stojanovic (1)
  Bojana Stamenkovic (1)
  Dejan Popovic (2)
  Sa?a Milenkovic (1)
  Milena Dimic (3)
  Jovan Nedovic (1)
  
• 关键词：Bone mineral density ; Cardiovascular risk ; Postmenopausal women ; Lipid status
• 刊名：Central European Journal of Medicine
• 出版年：2012
• 出版时间：October 2012
• 年：2012
• 卷：7
• 期：5
• 页码：642-649
• 全文大小：909KB
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• 作者单位：Aleksandar Dimic (1)
  Marina Ra?ic Popovic (2)
  Ivan Tasic (1)
  Dragan Djordjevic (1)
  Sonja Stojanovic (1)
  Bojana Stamenkovic (1)
  Dejan Popovic (2)
  Sa?a Milenkovic (1)
  Milena Dimic (3)
  Jovan Nedovic (1)
  
  1. Institute for Therapy & Rehabilitation, Niska Banja, Serbia, Faculty of Medicine, University of Nis, Bul. Dr Zorana Djindjica 81, 18000, Nis, Serbia
  2. Health Center Vranje, J. J. Lunge 1, 17500, Vranje, Serbia
  3. Faculty of Medicine, University of Nis, Bul. Dr Zorana Djindjica 81, 18000, Nis, Serbia
  

文摘

The aim of the paper was to examine the relation between bone density and certain parameters of lipid status in postmenopausal women. The research involved 300 women referred to densitometric examination as they belonged to the risk group of postmenopausal women. All the examinees had the following biochemical parameters determined: total cholesterol, triglycerides, HDL cholesterol, LDL cholesterol, glycemia, serum Ca and P. Univariate logistic regression analyses showed that each year of age, menopause duration, AH are significantly connected to risk increase for the appearance of osteopenia or osteoporosis. Increase in values of SBP, DBP, cholesterol, LDL and triglyceride are connected with significant risk increase for the appearance of osteopenia or osteoporosis. Patients with AH are connected to 11 times elevated risk for the appearance of osteopenia or osteoporosis, cigarette smoking increased the risk by seven times, physical inactivity even by 52 times, CVD in the family anamnesis by eight times, and osteoporosis in the family anamnesis is connected to the risk by four times. In our research, atherogenic lipoproteins negatively correlate with lumbar bone density. Disturbed lipide status is a risk factor for cardiovascular diseases, but also a risk factor for the appearance of osteoporosis.