One-Pot Synthesis of Dysprosium Oxide Nano-Sheets: Antimicrobial Potential and Cyotoxicity on A549 Lung Cancer Cells

详细信息    查看全文

• 作者：Kasi Gopinath ; Mari Chinnadurai ; Natarajan Parimala Devi…
• 关键词：Green synthesis ; Syzygium travancoricum ; Micro ; Raman analysis ; UV–VIS–DRS ; ATR ; FT ; IR
• 刊名：Journal of Cluster Science
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：28
• 期：1
• 页码：621-635
• 全文大小：
• 刊物类别：Chemistry and Materials Science
• 刊物主题：Catalysis; Inorganic Chemistry; Physical Chemistry; Nanochemistry;
• 出版者：Springer US
• ISSN：1572-8862
• 卷排序：28

文摘

The present work deals with green synthesis of dysprosium oxide nano-sheets (Dy₂O₃ NS) using Syzygium travancoricum leaf extract. Synthesized NS were characterized by UV–VIS–DRS, ATR-FT-IR, PL, Raman spectroscopy, XRD, TEM with EDX and XPS analysis. UV–VIS–DRS analysis showed the absorption peak at 355 nm and band gap value of 4.8 eV. ATR-FT-IR analysis was performed to analyze the biomolecules responsible for formation of Dy₂O₃ NS. Micro-Raman analysis showed a peak at 373 cm−1. XRD confirmed the presence of Dy₂O₃ NS with body-centered cubic structure. TEM images revealed the presence of nano sheets with size ranging from 100 to 200 nm and EDX analysis showed Dy and O elements and no other elements were detected, which indicates the purity of the resultant Dy₂O₃ NS. The synthesized Dy₂O₃ NS were tested against different bacterial and fungal species as well as cytotoxic agents on A549 lung cancer cells. The antimicrobial activity of Dy₂O₃ NS was significant on all the tested species. Cytotoxicity of Dy₂O₃ NS was revealed against A549 lung cancer cell lines in a dose-dependent manner. The results suggest that the synthesized Dy₂O₃ NS may be a promising candidate in the field of biomedical applications.