Frontier studies on fatigue, autonomic nerve dysfunction, and sleep-rhythm disorder
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- 作者：Masaaki Tanaka ; Seiki Tajima ; Kei Mizuno…
- 关键词：Autonomic nervous system ; Central nervous system ; Circadian rhythm ; Fatigue ; Sleep
- 刊名：The Journal of Physiological Sciences
- 出版年：2015
- 出版时间：November 2015
- 年：2015
- 卷：65
- 期：6
- 页码：483-498
- 全文大小：929 KB
- 参考文献：1.Kanaya N, Hirata N, Kurosawa S, Nakayama M, Namiki A (2003) Differential effects of propofol and sevoflurane on heart rate variability. Anesthesiology 98:34鈥?0PubMed CrossRef
2.Takusagawa M, Komori S, Umetani K, Ishihara T, Sawanobori T, Kohno I, Sano S, Yin D, Ijiri H, Tamura K (1999) Alterations of autonomic nervous activity in recurrence of variant angina. Heart 82:75鈥?1PubMedCentral PubMed CrossRef
3.No authors listed (1996) Heart rate variability: standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Circulation 93:1043鈥?065CrossRef
4.Akselrod S, Gordon D, Ubel FA, Shannon DC, Barger AC, Cohen RJ (1981) Power spectrum analysis of heart rate fluctuation: a quantitative probe of beat-to-beat cardiovascular control. Science 213:220鈥?22PubMed CrossRef
5.Pomeranz B, Macaulay RJ, Caudill MA, Kutz I, Adam D, Gordon D, Kilborn KM, Barger AC, Shannon DC, Cohen RJ et al (1985) Assessment of autonomic function in humans by heart rate spectral analysis. Am J Physiol 248:151鈥?53
6.Malliani A, Pagani M, Lombardi F, Cerutti S (1991) Cardiovascular neural regulation explored in the frequency domain. Circulation 84:482鈥?92PubMed CrossRef
7.Appel ML, Berger RD, Saul JP, Smith JM, Cohen RJ (1989) Beat to beat variability in cardiovascular variables: noise or music? J Am Coll Cardiol 14:1139鈥?148PubMed CrossRef
8.Pagani M, Montano N, Porta A, Malliani A, Abboud FM, Birkett C, Somers VK (1997) Relationship between spectral components of cardiovascular variabilities and direct measures of muscle sympathetic nerve activity in humans. Circulation 95:1441鈥?448PubMed CrossRef
9.Tanaka M, Mizuno K, Tajima S, Sasabe T, Watanabe Y (2009) Central nervous system fatigue alters autonomic nerve activity. Life Sci 84:235鈥?39PubMed CrossRef
10.Tanaka M, Mizuno K, Yamaguti K, Kuratsune H, Fujii A, Baba H, Matsuda K, Nishimae A, Takesaka T, Watanabe Y (2011) Autonomic nervous alterations associated with daily level of fatigue. Behav Brain Funct 7:46PubMedCentral PubMed CrossRef
11.Mizuno K, Tanaka M, Yamaguti K, Kajimoto O, Kuratsune H, Watanabe Y (2011) Mental fatigue caused by prolonged cognitive load associated with sympathetic hyperactivity. Behav Brain Funct 7:17PubMedCentral PubMed CrossRef
12.Chalder T, Berelowitz G, Pawlikowska T, Watts L, Wessely S, Wright D, Wallace EP (1993) Development of a fatigue scale. J Psychosom Res 37:147鈥?53PubMed CrossRef
13.Tanaka M, Fukuda S, Mizuno K, Kuratsune H, Watanabe Y (2009) Stress and coping styles are associated with severe fatigue in medical students. Behav Med 35:87鈥?2PubMed CrossRef
14.Tanaka M, Fukuda S, Mizuno K, Imai-Matsumura K, Jodoi T, Kawatani J, Takano M, Miike T, Tomoda A, Watanabe Y (2008) Reliability and validity of the Japanese version of the Chalder Fatigue Scale among youth in Japan. Psychol Rep 103:682鈥?90PubMed
15.Afari N, Buchwald D (2003) Chronic fatigue syndrome: a review. Am J Psychiatry 160:221鈥?36PubMed CrossRef
16.Wyller VB, Saul JP, Amlie JP, Thaulow E (2007) Sympathetic predominance of cardiovascular regulation during mild orthostatic stress in adolescents with chronic fatigue. Clin Physiol Funct Imaging 27:231鈥?38PubMed CrossRef
17.Burton AR, Rahman K, Kadota Y, Lloyd A, Vollmer-Conna U (2010) Reduced heart rate variability predicts poor sleep quality in a case鈥揷ontrol study of chronic fatigue syndrome. Exp Brain Res 204:71鈥?8PubMed CrossRef
18.Yamaguti K, Sasabe T, Kuratsune H, Nishizawa Y, Watanabe Y (2008) J Therapy 90:537鈥?47 (in Japanese)
19.Tomoda A, Mizuno K, Murayama N, Joudoi T, Igasaki T, Miyazaki M, Miike T (2007) Event-related potentials in Japanese childhood chronic fatigue syndrome. J Pediatr Neurol 5:199鈥?08
20.Benarroch EE (1997) The central autonomic network. In: Low PA (ed) Clinical autonomic disorder, 2nd edn. Lippincott-Raven, Philadelphia
21.Loewy AD (1990) Central autonomic pathways. In: Loewy AD, Spyer KM (eds) Central regulation of autonomic functions. Oxford Univ Press, New York
22.Critchley HD, Mathias CJ, Josephs O, O鈥橠oherty J, Zanini S, Dewar BK, Cipolotti L, Shallice T, Dolan RJ (2003) Human cingulate cortex and autonomic control: converging neuroimaging and clinical evidence. Brain 126:2139鈥?152PubMed CrossRef
23.Koski L, Paus T (2000) Functional connectivity of the anterior cingulate cortex within the human frontal lobe: a brain-mapping meta-analysis. Exp Brain Res 133:55鈥?5PubMed CrossRef
24.Paus T, Castro-Alamancos MA, Petrides M (2001) Cortico-cortical connectivity of the human mid-dorsolateral frontal cortex and its modulation by repetitive transcranial magnetic stimulation. Eur J Neurosci 14:1405鈥?411PubMed CrossRef
25.Petrides M, Pandya DN (1999) Dorsolateral prefrontal cortex: comparative cytoarchitectonic analysis in the human and the macaque brain and corticocortical connection patterns. Eur J Neurosci 11:1011鈥?036PubMed CrossRef
26.Vogt BA, Pandya DN (1987) Cingulate cortex of the rhesus monkey: II. Cortical afferents. J Comp Neurol 262:271鈥?89PubMed CrossRef
27.Amat J, Baratta MV, Paul E, Bland ST, Watkins LR, Maier SF (2005) Medial prefrontal cortex determines how stressor controllability affects behavior and dorsal raphe nucleus. Nat Neurosci 8:365鈥?71PubMed CrossRef
28.Thayer JF, Sternberg E (2006) Beyond heart rate variability: vagal regulation of allostatic systems. Ann N Y Acad Sci 1088:361鈥?72PubMed CrossRef
29.Thayer JF (2006) On the importance of inhibition: central and peripheral manifestations of nonlinear inhibitory processes in neural systems. Dose Response 4:2鈥?1PubMedCentral PubMed CrossRef
30.Boksem MA, Meijman TF, Lorist MM (2006) Mental fatigue, motivation and action monitoring. Biol Psychol 72:123鈥?32PubMed CrossRef
31.Tanaka M, Sadato N, Okada T, Mizuno K, Sasabe T, Tanabe HC, Saito DN, Onoe H, Kuratsune H, Watanabe Y (2006) Reduced responsiveness is an essential feature of chronic fatigue syndrome: a fMRI study. BMC Neurol 6:9PubMedCentral PubMed CrossRef
32.Mizuno K, Tanaka M, Tanabe HC, Sadato N, Watanabe Y (2012) The neural substrates associated with attentional resources and difficulty of concurrent processing of the two verbal tasks. Neuropsychologia 50:1998鈥?009PubMed CrossRef
33.Tajima S, Yamamoto S, Tanaka M, Kataoka Y, Iwase M, Yoshikawa E, Okada H, Onoe H, Tsukada H, Kuratsune H, Ouchi Y, Watanabe Y (2010) Medial orbitofrontal cortex is associated with fatigue sensation. Neurol Res Int 2010:671421PubMedCentral PubMed
34.Caseras X, Mataix-Cols D, Rimes KA, Giampietro V, Brammer M, Zelaya F, Chalder T, Godfrey E (2008) The neural correlates of fatigue: an exploratory imaginal fatigue provocation study in chronic fatigue syndrome. Psychol Med 38:941鈥?51PubMed
35.Okada T, Tanaka M, Kuratsune H, Watanabe Y, Sadato N (2004) Mechanisms underlying fatigue: a voxel-based morphometric study of chronic fatigue syndrome. BMC Neurol 4:14PubMedCentral PubMed CrossRef
36.Mizuno K, Tajima K, Watanabe Y, Kuratsune H (2014) Fatigue correlates with the decrease in parasympathetic sinus modulation induced by a cognitive challenge. Behav Brain Funct 10:25PubMedCentral PubMed CrossRef
37.Mizuno K, Tanaka M, Fukuda S, Imai-Matsumura K, Watanabe Y (2011) Relationship between cognitive functions and prevalence of fatigue in elementary and junior high school students. Brain Dev 33:470鈥?79PubMed CrossRef
38.Tajima K, Tanaka M, Mizuno K, Okada N, Rokushima K, Watanabe Y (2008) Effects of bathing in micro-bubbles on recovery from moderate mental fatigue. Ergonomia IJE&HF 30:134鈥?45
39.Watanabe Y, Sasabe T, Yamaguti K, Kobayashi M, Yamamoto S, Kuratsune H, Sano K, Hatanaka A, Tsukada H, Onoe H (2005) Prevention and/or recovery effects by green odor(s) on fatigue and green-odor-responsible brain regions as revealed by PET. Chem Senses Suppl 1:i268鈥搃269CrossRef
40.Sasabe T, Kobayashi M, Kondo Y, Onoe H, Matsubara S, Yamamoto S, Tsukada H, Onoe K, Watabe H, Iida H, Kogo M, Sano K, Hatanaka A, Sawada T, Watanabe Y (2003) Activation of the anterior cingulate gyrus by 鈥楪reen Odor鈥? a positron emission tomography study in the monkey. Chem Senses 28:565鈥?72PubMed CrossRef
41.Morriss R, Sharpe M, Sharpley AL, Cowen PJ, Hawton K, Morris J (1993) Abnormalities of sleep in patients with the chronic fatigue syndrome. BMJ 306:1161鈥?164PubMedCentral PubMed CrossRef
42.Watson NF, Kapur V, Arguelles LM, Goldberg J, Schmidt DF, Armitage R, Buchwald D (2003) Comparison of subjective and objective measures of insomnia in monozygotic twins discordant for chronic fatigue syndrome. Sleep 26:324鈥?28PubMed
43.Watson NF, Jacobsen C, Goldberg J, Kapur V, Buchwald D (2004) Subjective and objective sleepiness in monozygotic twins discordant for chronic fatigue syndrome. Sleep 27:973鈥?77PubMed
44.Neu D, Mairesse O, Hoffmann G, Dris A, Lambrecht LJ, Linkowski P, Verbanck P, Le Bon O (2007) Sleep quality perception in the chronic fatigue syndrome: correlations with sleep efficiency, affective symptoms and intensity of fatigue. Neuropsychobiology 56:40鈥?6PubMed CrossRef
45.Armitage R, Landis C, Hoffmann R, Lentz M, Watson N, Goldberg J, Buchwald D (2009) Power spectral analysis of sleep EEG in twins discordant for chronic fatigue syndrome. J Psychosom Res 66:51鈥?7PubMedCentral PubMed CrossRef
46.Rahman K, Burton A, Galbraith S, Lloyd A, Vollmer-Conna U (2011) Sleep-wake behavior in chronic fatigue syndrome. Sleep 34:671鈥?78PubMedCentral PubMed
47.Morriss RK, Wearden AJ, Battersby L (1997) The relation of sleep difficulties to fatigue, mood and disability in chronic fatigue syndrome. J Psychosom Res 42:597鈥?05PubMed CrossRef
48.Unger ER, Nisenbaum R, Moldofsky H, Cesta A, Sammut C, Reyes M, Reeves WC (2004) Sleep assessment in a population-based study of chronic fatigue syndrome. BMC Neurol 19:6CrossRef
49.Kop WJ, Lyden A, Berlin AA, Ambrose K, Olsen C, Gracely RH, Williams DA, Clauw DJ (2005) Ambulatory monitoring of physical activity and symptoms in fibromyalgia and chronic fatigue syndrome. Arthritis Rheum 52:296鈥?03PubMed CrossRef
50.Hossain JL, Reinish LW, Kayumov L, Bhuiya P, Shapiro CM (2003) Underlying sleep pathology may cause chronic high fatigue in shift-workers. J Sleep Res 12:223鈥?30PubMed CrossRef
51.Sharpley A, Clements A, Hawton K, Sharpe M (1997) Do patients with 鈥減ure鈥?chronic fatigue syndrome (neurasthenia) have abnormal sleep? Psychosom Med 59:592鈥?96PubMed CrossRef
52.Stores G, Fry A, Crawford C (1998) Sleep abnormalities demonstrated by home polysomnography in teenagers with chronic fatigue syndrome. J Psychosom Res 45:85鈥?1PubMed CrossRef
53.Tajima S, Kuratsune H, Yamaguti K, Takahashi A, Takashima S, Watanabe Y, Nishizawa Y (2007) Estimation of fatigue state in patient with CFS using actigraph and R-R interval power spectrum analysis. Nihon Rinsho 65:1057鈥?064 (in Japanese) PubMed
54.Ohinata J, Suzuki N, Araki A, Takahashi S, Fujieda K, Tanaka H (2008) Actigraphic assessment of sleep disorders in children with chronic fatigue syndrome. Brain Dev 30:329鈥?33PubMed CrossRef
55.Aerenhouts D, Ickmans K, Clarys P, Zinzen E, Meersdom G, Lambrecht L, Nijs J (2014) Sleep characteristics, exercise capacity and physical activity in patients with chronic fatigue syndrome. Disabil Rehabil 16:1鈥?
56.Ball N, Buchwald DS, Schmidt D, Goldberg J, Ashton S, Armitage R (2004) Monozygotic twins discordant for chronic fatigue syndrome: objective measures of sleep. J Psychosom Res 56:207鈥?12PubMed CrossRef
57.Fossey M, Libman E, Bailes S, Baltzan M, Schondorf R, Amsel R, Fichten CS (2004) Sleep quality and psychological adjustment in chronic fatigue syndrome. J Behav Med 27:581鈥?05PubMed CrossRef
58.Reeves WC, Heim C, Maloney EM, Youngblood LS, Unger ER, Decker MJ, Jones JF, Rye DB (2006) Sleep characteristics of persons with chronic fatigue syndrome and non-fatigued controls: results from a population-based study. BMC Neurol 16:41CrossRef
59.Guilleminault C, Poyares D, Rosa Ad, Kirisoglu C, Almeida T, Lopes MC (2006) Chronic fatigue, unrefreshing sleep and nocturnal polysomnography. Sleep Med 7:513鈥?20PubMed CrossRef
60.Kishi A, Struzik ZR, Natelson BH, Togo F, Yamamoto Y (2008) Dynamics of sleep stage transitions in healthy humans and patients with chronic fatigue syndrome. Am J Physiol Regul Integr Comp Physiol 294:R1980鈥揜1987PubMed CrossRef
61.Decker MJ, Tabassum H, Lin JM, Reeves WC (2009) Electroencephalographic correlates of chronic fatigue syndrome. Behav Brain Funct 6:43CrossRef
62.Neu D, Cappeliez B, Hoffmann G, Verbanck P, Linkowski P, Le Bon O (2009) High slow-wave sleep and low-light sleep: chronic fatigue syndrome is not likely to be a primary sleep disorder. J Clin Neurophysiol 26:207鈥?12PubMed CrossRef
63.Le Bon O, Neu D, Berquin Y, Lanquart JP, Hoffmann R, Mairesse O, Armitage R (2012) Ultra-slow delta power in chronic fatigue syndrome. Psychiatry Res 200:742鈥?47PubMed CrossRef
64.Neu D, Mairesse O, Verbanck P, Le Bon O (2015) Slow wave sleep in the chronically fatigued: Power spectra distribution patterns in chronic fatigue syndrome and primary insomnia. Clin Neurophysiol. doi:10.鈥?016/鈥媕.鈥媍linph.鈥?014.鈥?2.鈥?16 PubMed
65.Kishi A, Natelson BH, Togo F, Struzik ZR, Rapoport DM, Yamamoto Y (2011) Sleep-stage dynamics in patients with chronic fatigue syndrome with or without fibromyalgia. Sleep 34:1551鈥?560PubMedCentral PubMed
66.Gotts ZM, Deary V, Newton J, Van der Dussen D, De Roy P, Ellis JG (2013) Are there sleep-specific phenotypes in patients with chronic fatigue syndrome? A cross-sectional polysomnography analysis. BMJ Open. doi:10.鈥?136/鈥媌mjopen-2013-002999 PubMedCentral PubMed
67.Mariman A, Vogelaers D, Hanoulle I, Delesie L, Pevernagie D (2012) Subjective sleep quality and daytime sleepiness in a large sample of patients with chronic fatigue syndrome (CFS). Acta Clin Belg 67:19鈥?4PubMed
68.Togo F, Natelson BH, Cherniack NS, FitzGibbons J, Garcon C, Rapoport DM (2008) Sleep structure and sleepiness in chronic fatigue syndrome with or without coexisting fibromyalgia. Arthritis Res Ther 10:R56PubMedCentral PubMed CrossRef
69.Ohashi K, Yamamoto Y, Natelson BH (2002) Activity rhythm degrades after strenuous exercise in chronic fatigue syndrome. Physiol Behav 77:39鈥?4PubMed CrossRef
70.Togo F, Natelson BH, Cherniack NS, Klapholz M, Rapoport DM, Cook DB (2010) Sleep is not disrupted by exercise in patients with chronic fatigue syndromes. Med Sci Sports Exerc 42:16鈥?2PubMedCentral PubMed CrossRef
71.Kishi A, Togo F, Cook DB, Klapholz M, Yamamoto Y, Rapoport DM, Natelson BH (2013) The effects of exercise on dynamic sleep morphology in healthy controls and patients with chronic fatigue syndrome. Physiol Rep 1:e00152PubMedCentral PubMed CrossRef
72.Tomoda A, Miike T, Uezono K, Kawasaki T (1994) A school refusal case with biological rhythm disturbance and melatonin therapy. Brain Dev 16:71鈥?6PubMed CrossRef
73.van Heukelom RO, Prins JB, Smits MG, Bleijenberg G (2006) Influence of melatonin on fatigue severity in patients with chronic fatigue syndrome and late melatonin secretion. Eur J Neurol 13:55鈥?0PubMed CrossRef
74.Williams G, Pirmohamed J, Minors D, Waterhouse J, Buchan I, Arendt J, Edwards RH (1996) Dissociation of body-temperature and melatonin secretion circadian rhythms in patients with chronic fatigue syndrome. Clin Physiol 16:327鈥?37PubMed CrossRef
75.Tomoda A, Miike T, Yonamine K, Adachi K, Shiraishi S (1997) Disturbed circadian core body temperature rhythm and sleep disturbance in school refusal children and adolescents. Biol Psychiatry 41:810鈥?13PubMed CrossRef
76.Hamilos DL, Nutter D, Gershtenson J, Ikle D, Hamilos SS, Redmond DP, Di Clementi JD, Schmaling KB, Jones JF (2001) Circadian rhythm of core body temperature in subjects with chronic fatigue syndrome. Clin Physiol 21:184鈥?95PubMed CrossRef
77.Ohashi K, Bleijenberg G, van der Werf S, Prins J, Amaral LA, Natelson BH, Yamamoto Y (2004) Decreased fractal correlation in diurnal physical activity in chronic fatigue syndrome. Methods Inf Med 43:26鈥?9PubMed
78.Tajima S (2009) Physiological fatigue estimation using physical activity analysis. Igaku No Ayumi 228:640鈥?45 (in Japanese)
79.Kawabata M, Ueno T, Tomita J, Kawatani J, Tomoda A, Kume S, Kume K (2013) Temporal organization of rest defined by actigraphy data in healthy and childhood chronic fatigue syndrome children. BMC Psychiatry 13:281PubMedCentral PubMed CrossRef
80.Takimoto M, Hamada A, Tomoda A, Ohdo S, Ohmura T, Sakato H, Kawatani J, Jodoi T, Nakagawa H, Terazono H, Koyanagi S, Higuchi S, Kimura M, Tukikawa H, Irie S, Saito H, Miike T (2005) Daily expression of clock genes in whole blood cells in healthy subjects and a patient with circadian rhythm sleep disorder. Am J Physiol Regul Integr Comp Physiol 289:R1273鈥揜1279PubMed CrossRef
81.Boneva RS, Decker MJ, Maloney EM, Lin JM, Jones JF, Helgason HG, Heim CM, Rye DB, Reeves WC (2007) Higher heart rate and reduced heart rate variability persist during sleep in chronic fatigue syndrome: a population-based study. Auton Neurosci 137:94鈥?01PubMed CrossRef
82.Yamaguti K, Tajima S, Kuratsune H (2013) Autonomic dysfunction in chronic fatigue syndrome. Adv Neuroimmun Biol 4:281鈥?89
83.Tomoda A, Miike T, Honda T, Fukuda K, Kai Y, Nabeshima M, Takahashi M (1995) Single-photon emission computed tomography for cerebral blood flow in school phobia. Curr Ther Res 56:1088鈥?093CrossRef
84.Tomoda A, Miike T, Yamada E, Honda H, Moroi T, Ogawa M, Ohtani Y, Morishita S (2000) Chronic fatigue syndrome in childhood. Brain Dev 22:60鈥?4PubMed CrossRef
85.Gotts ZM, Ellis JG, Deary V, Barclay N, Newton JL (2015) The association between daytime napping and cognitive functioning in chronic fatigue syndrome. PLoS One 10:e0117136. doi:10.鈥?371/鈥媕ournal.鈥媝one.鈥?117136 PubMedCentral PubMed CrossRef
86.Richards RS, Roberts TK, McGregor NR, Dunstan RH, Butt HL (2000) Blood parameters indicative of oxidative stress are associated with symptom expression in chronic fatigue syndrome. Redox Rep 5:35鈥?1PubMed CrossRef
87.Tomoda A, Joudoi T, el-M Rabab, Matsumoto T, Park TH, Miike T (2005) Cytokine production and modulation: comparison of patients with chronic fatigue syndrome and normal controls. Psychiatry Res 134:101鈥?04PubMed CrossRef
88.Nakamura T, Schwander S, Donnelly R, Cook DB, Ortega F, Togo F, Yamamoto Y, Cherniack NS, Klapholz M, Rapoport D, Natelson BH (2013) Exercise and sleep deprivation do not change cytokine expression levels in patients with chronic fatigue syndrome. Clin Vaccine Immunol 20:1736鈥?742PubMedCentral PubMed CrossRef
89.Iwatani N, Miike T, Kai Y, Kodama M, Mabe H, Tomoda A, Fukuda K, Jyodoi T (1997) Glucoregulatory disorders in school refusal students. Clin Endocrinol 47:273鈥?78CrossRef
90.Taylor JL, Gandevia SC (2008) A comparison of central aspects of fatigue in submaximal and maximal voluntary contractions. J Appl Physiol 104:542鈥?50PubMed CrossRef
91.Taylor JL, Butler JE, Allen GM, Gandevia SC (1996) Changes in motor cortical excitability during human muscle fatigue. J Physiol 490:519鈥?28PubMedCentral PubMed CrossRef
92.Johnston J, Rearick M, Slobounov S (2001) Movement-related cortical potentials associated with progressive muscle fatigue in a grasping task. Clin Neurophysiol 112:68鈥?7PubMed CrossRef
93.Liu JZ, Lewandowski B, Karakasis C, Yao B, Siemionow V, Sahgal V, Yue GH (2007) Shifting of activation center in the brain during muscle fatigue: an explanation of minimal central fatigue? Neuroimage 35:299鈥?07PubMedCentral PubMed CrossRef
94.Dettmers C, Lemon RN, Stephan KM, Fink GR, Frackowiak RS (1996) Cerebral activation during the exertion of sustained static force in man. Neuroreport 7:2103鈥?110PubMed CrossRef
95.Korotkov A, Radovanovic S, Ljubisavljevic M, Lyskov E, Kataeva G, Roudas M, Pakhomov S, Thunberg J, Medvedev S, Johansson H (2005) Comparison of brain activation after sustained non-fatiguing and fatiguing muscle contraction: a positron emission tomography study. Exp Brain Res 163:65鈥?4PubMed CrossRef
96.Liu JZ, Shan ZY, Zhang LD, Sahgal V, Brown RW, Yue GH (2003) Human brain activation during sustained and intermittent submaximal fatigue muscle contractions: an FMRI study. J Neurophysiol 90:300鈥?12PubMed CrossRef
97.Benwell NM, Mastaglia FL, Thickbroom GW (2006) Reduced functional activation after fatiguing exercise is not confined to primary motor areas. Exp Brain Res 175:575鈥?83PubMed CrossRef
98.Benwell NM, Mastaglia FL, Thickbroom GW (2007) Changes in the functional MR signal in motor and non-motor areas during intermittent fatiguing hand exercise. Exp Brain Res 18:93鈥?7CrossRef
99.Post M, Steens A, Renken R, Maurits NM, Zijdewind I (2009) Voluntary activation and cortical activity during a sustained maximal contraction: an fMRI study. Hum Brain Mapp 30:1014鈥?027PubMed CrossRef
100.Logothetis NK (2008) What we can do and what we cannot do with fMRI. Nature 453:869鈥?78PubMed CrossRef
101.Shibasaki H (2008) Human brain mapping: hemodynamic response and electrophysiology. Clin Neurophysiol 119:731鈥?43PubMed CrossRef
102.Tanji J, Okano K, Sato KC (1988) Neuronal activity in cortical motor areas related to ipsilateral, contralateral, and bilateral digit movements of the monkey. J Neurophysiol 60:325鈥?43PubMed
103.Tanaka M, Ishii A, Watanabe Y (2013) Neural mechanism of facilitation system during physical fatigue. PLoS One 8:80731CrossRef
104.Tanaka M, Watanabe Y (2011) Neural compensation mechanisms to regulate motor output during physical fatigue. Brain Res 1395:46鈥?2PubMed CrossRef
105.Tanaka M, Ishii A, Watanabe Y (2014) Regulatory mechanism of performance in chronic cognitive fatigue. Med Hypotheses 82:567鈥?71PubMed CrossRef
106.Alexander GE, Crutcher MD (1990) Functional architecture of basal ganglia circuits: neural substrates of parallel processing. Trends Neurosci 13:266鈥?71PubMed CrossRef
107.Tanaka M, Watanabe Y (2012) Supraspinal regulation of physical fatigue. Neurosci Biobehav Rev 36:727鈥?34PubMed CrossRef
108.Desmond P, Hancock P (2001) Active and passive fatigue states. In: Hancock P, Desmond P (eds) Stress, workload, and fatigue. Lawrence Erlbaum Associates, New Jersey
109.Matthews G, Desmond PA (2002) Task-induced fatigue states and simulated driving performance. Q J Exp Psychol A 55:659鈥?86PubMed CrossRef
110.Mizuno K, Watanabe Y (2007) Utility of an advanced trail making test as a neuropsychological tool for an objective evaluation of work efficiency during mental fatigue. In: Watanabe Y, Eveng氓rd B, Natelson B, Jason L, Kuratsune H (eds) Fatigue science for human health. Springer, New York
111.Tanaka M, Ishii A, Watanabe Y (2014) Neural effects of mental fatigue caused by continuous attention load: a magnetoencephalography study. Brain Res 1561:60鈥?6PubMed CrossRef
112.Ishii A, Tanaka M, Shigihara Y, Kanai E, Funakura M, Watanabe Y (2013) Neural effects of prolonged mental fatigue: a magnetoencephalography study. Brain Res 1529:105鈥?12PubMed CrossRef
113.Shigihara Y, Tanaka M, Ishii A, Tajima S, Kanai E, Funakura M, Watanabe Y (2013) Two different types of mental fatigue produce different styles of task performance. Neurol Psychiatr Brain Res 19:5鈥?1CrossRef
114.Shigihara Y, Tanaka M, Ishii A, Kanai E, Funakura M, Watanabe Y (2013) Two types of mental fatigue affect spontaneous oscillatory brain activities in different ways. Behav Brain Funct 9:2PubMedCentral PubMed CrossRef
115.Tanaka M, Ishii A, Shigihara Y, Tajima S, Funakura M, Kanai E, Watanabe Y (2012) Impaired selective attention caused by mental fatigue. J Neurol Sci (Turkish) 29:542鈥?53
116.Tanaka M, Shigihara Y, Ishii A, Funakura M, Kanai E, Watanabe Y (2012) Effect of mental fatigue on the central nervous system: an electroencephalography study. Behav Brain Funct 8:48PubMedCentral PubMed CrossRef
117.Kuratsune D, Tajima S, Koizumi J, Yamaguti K, Sasabe T, Mizuno K, Tanaka M, Okawa N, Mito H, Tsubone H, Watanabe Y, Inoue M, Kuratsune H (2012) Changes in reaction time, coefficient of variance of reaction time, and autonomic nerve function in the mental fatigue state caused by long-term computerized Kraepelin test workload in healthy volunteers. World J Neurosci 2:113鈥?18CrossRef
118.Shigihara Y, Tanaka M, Watanabe Y (2010) Relationship between fatigue and photosensitivity. Behav Med 36:109鈥?12PubMed CrossRef
119.Kajimoto O (2007) Development of a method of evaluation of fatigue and its economic impacts. In: Watanabe Y, Eveng氓rd B, Natelson B, Jason L, Kuratsune H (eds) Fatigue science for human health. Springer, New York
120.Johnson SA, Yechiam E, Murphy RR, Queller S, Stout JC (2006) Motivational processes and autonomic responsivity in Asperger鈥檚 disorder: evidence from the Iowa Gambling Task. JINS 12:668鈥?76PubMed
121.Mezzacappa E, Kindlon D, Saul JP, Earls F (1998) Executive and motivational control of performance task behavior, and autonomic heart-rate regulation in children: physiologic validation of two-factor solution inhibitory control. J Child Psychol Psychiatry 39:525鈥?31PubMed CrossRef
122.Brookes MJ, Wood JR, Stevenson CM, Zumer JM, White TP, Liddle PF, Morris PG (2011) Changes in brain network activity during working memory tasks: a magnetoencephalography study. Neuroimage 55:1804鈥?815PubMed CrossRef
123.Varela F, Lachaux JP, Rodriguez E, Martinerie J (2001) The brainweb: phase synchronization and large-scale integration. Nat Rev Neurosci 2:229鈥?39PubMed CrossRef
124.Lopes da Silva F (1991) Neural mechanisms underlying brain waves: from neural membranes to networks. Electroencephalogr Clin Neurophysiol 79:81鈥?3PubMed CrossRef
125.Rinzel J, Terman D, Wang X, Ermentrout B (1998) Propagating activity patterns in large-scale inhibitory neuronal networks. Science 279:1351鈥?355PubMed CrossRef
126.Yanagisawa H, Dan I, Tsuzuki D, Kato M, Okamoto M, Kyutoku Y, Soya H (2010) Acute moderate exercise elicits increased dorsolateral prefrontal activation and improves cognitive performance with Stroop test. Neuroimage 50:1702鈥?710PubMed CrossRef
127.Tanaka M, Ishii A, Watanabe Y (2014) Neural effect of mental fatigue on physical fatigue: a magnetoencephalography study. Brain Res 1542:49鈥?5PubMed CrossRef
128.Boksem MA, Tops M (2008) Mental fatigue: costs and benefits. Brain Res Rev 59:125鈥?39PubMed CrossRef
129.Lim J, Wu WC, Wang J, Detre JA, Dinges DF, Rao H (2010) Imaging brain fatigue from sustained mental workload: an ASL perfusion study of the time-on-task effect. Neuroimage 49:3426鈥?435PubMedCentral PubMed CrossRef
130.Ishii A, Tanaka M, Watanabe Y (2014) Neural mechanisms of mental fatigue. Rev Neurosci 25:469鈥?79PubMed
131.Smith EE, Jonides J (1999) Storage and executive processes in the frontal lobes. Science 283:1657鈥?661PubMed CrossRef
132.Carter CS, van Veen V (2007) Anterior cingulate cortex and conflict detection: an update of theory and data. Cogn Affect Behav Neurosci 7:367鈥?79PubMed CrossRef
133.Chaudhuri A, Behan PO (2000) Fatigue and basal ganglia. J Neurol Sci 179:34鈥?2PubMed CrossRef
134.Chaudhuri A, Behan PO (2004) Fatigue in neurological disorders. Lancet 363:978鈥?88PubMed CrossRef
135.Roelcke U, Kappos L, Lechner-Scott J, Brunnschweiler H, Huber S, Ammann W, Plohmann A, Dellas S, Maguire RP, Missimer J, Radu EW, Steck A, Leenders KL (1997) Reduced glucose metabolism in the frontal cortex and basal ganglia of multiple sclerosis patients with fatigue: a 18F-fluorodeoxyglucose positron emission tomography study. Neurology 48:1566鈥?571PubMed CrossRef
136.Filippi M, Rocca MA, Colombo B, Falini A, Codella M, Scotti G, Comi G (2002) Functional magnetic resonance imaging correlates of fatigue in multiple sclerosis. Neuroimage 15:559鈥?67PubMed CrossRef
137.White AT, Lee JN, Light AR, Light KC (2009) Brain activation in multiple sclerosis: a BOLD fMRI study of the effects of fatiguing hand exercise. Mult Scler 15:580鈥?86PubMed CrossRef
138.Sisto SA, LaManca J, Cordero DL, Bergen MT, Ellis SP, Drastal S, Boda WL, Tapp WN, Natelson BH (1996) Metabolic and cardiovascular effects of a progressive exercise test in patients with chronic fatigue syndrome. Am J Med 100:634鈥?40PubMed CrossRef
139.Gibson H, Carroll N, Clague JE, Edwards RH (1993) Exercise performance and fatiguability in patients with chronic fatigue syndrome. J Neurol Neurosurg Psychiatry 56:993鈥?98PubMedCentral PubMed CrossRef
140.Chaudhuri A, Condon BR, Gow JW, Brennan D, Hadley DM (2003) Proton magnetic resonance spectroscopy of basal ganglia in chronic fatigue syndrome. Neuroreport 14:225鈥?28PubMed CrossRef
141.Kuratsune H, Yamaguti K, Lindh G, Eveng氓rd B, Hagberg G, Matsumura K, Iwase M, Onoe H, Takahashi M, Machii T, Kanakura Y, Kitani T, L氓ngstr枚m B, Watanabe Y (2002) Brain regions involved in fatigue sensation: reduced acetylcarnitine uptake into the brain. Neuroimage 17:1256鈥?265PubMed CrossRef
142.Siessmeier T, Nix WA, Hardt J, Schreckenberger M, Egle UT, Bartenstein P (2003) Observer independent analysis of cerebral glucose metabolism in patients with chronic fatigue syndrome. J Neurol Neurosurg Psychiatry 74:922鈥?28PubMedCentral PubMed CrossRef
143.de Lange FP, Koers A, Kalkman JS, Bleijenberg G, Hagoort P, van der Meer JW, Toni I (2008) Increase in prefrontal cortical volume following cognitive behavioural therapy in patients with chronic fatigue syndrome. Brain 131:2172鈥?180PubMed CrossRef
144.Tirelli U, Chierichetti F, Tavio M, Simonelli C, Bianchin G, Zanco P, Ferlin G (1998) Brain positron emission tomography (PET) in chronic fatigue syndrome: preliminary data. Am J Med 105:54鈥?8CrossRef
145.Shigihara Y, Tanaka M, Mizuno K, Ishii A, Yamano E, Funakura M, Kanai E, Watanabe Y (2012) Effects of daily levels of fatigue and acutely induced fatigue on the visual evoked magnetic response. Brain Res 1457:44鈥?0PubMed CrossRef
146.Tanaka M, Shigihara Y, Funakura M, Kanai E, Watanabe Y (2012) Fatigue-associated alterations of cognitive function and electroencephalographic power densities. PLoS One 7:34774CrossRef
147.Shigihara Y, Tanaka M, Tsuyuguchi N, Tanaka H, Watanabe Y (2010) Hazardous nature of high-temporal-frequency strobe light stimulation: neural mechanisms revealed by magnetoencephalography. Neuroscience 166:482鈥?90PubMed CrossRef
148.Tanaka M, Ishii A, Watanabe Y (2014) Hazardous effects of light stimulation in the central nervous system. Austin J Clin Neurol 1:4
149.Lipton P (1999) Ischemic cell death in brain neurons. Physiol Rev 79:1431鈥?568PubMed
150.Yamano E, Tanaka M, Ishii A, Tsuruoka N, Abe K, Watanabe Y (2013) Effects of chicken essence on recovery from mental fatigue in healthy males. Med Sci Monit 19:540鈥?47PubMedCentral PubMed CrossRef
151.Mizuma H, Tanaka M, Nozaki S, Mizuno K, Tahara T, Ataka S, Sugino T, Shirai T, Kajimoto Y, Kuratsune H, Kajimoto O, Watanabe Y (2009) Daily oral administration of crocetin attenuates physical fatigue in human. Nutr Res 29:145鈥?50PubMed CrossRef
152.Tanaka M, Baba Y, Kataoka Y, Kinbara N, Sagesaka YM, Kakuda T, Watanabe Y (2008) Effects of (-)-epigallocatechin gallate in liver of an animal model of combined (physical and mental) fatigue. Nutrition 24:599鈥?03PubMed CrossRef
153.Tanaka M, Watanabe Y (2008) Reduced energy utilization in the brain is a feature of an animal model of fatigue. Int J Neurosci 118:683鈥?92PubMed CrossRef
154.Mizuno K, Tanaka M, Nozaki S, Mizuma H, Ataka S, Tahara T, Sugino T, Shirai T, Kajimoto Y, Kuratsune H, Kajimoto O, Watanabe Y (2008) Antifatigue effects of coenzyme Q10 during physical fatigue. Nutrition 24:293鈥?99PubMed CrossRef
155.Ataka S, Tanaka M, Nozaki S, Mizuma H, Mizuno K, Tahara T, Sugino T, Shirai T, Kajimoto Y, Kuratsune H, Kajimoto O, Watanabe Y (2008) Effects of oral administration of caffeine and D-ribose on mental fatigue. Nutrition 24:233鈥?38PubMed CrossRef
156.Ataka S, Tanaka M, Nozaki S, Mizuma H, Mizuno K, Tahara T, Sugino T, Shirai T, Kajimoto Y, Kuratsune H, Kajimoto O, Watanabe Y (2007) Effects of Applephenon and ascorbic acid on physical fatigue. Nutrition 23:419鈥?23PubMed CrossRef
157.Mizokawa S, Tanaka M, Matsumura A, Nozaki S, Watanabe Y (2003) Recovery from fatigue: changes in local brain 2-[18F]fluoro-2-deoxy-d -glucose utilization measured by autoradiography and in brain monoamine levels of rat. Neurosci Lett 353:169鈥?72PubMed CrossRef
158.Tanaka M, Nakamura F, Mizokawa S, Matsumura A, Nozaki S, Watanabe Y (2003) Establishment and assessment of a rat model of fatigue. Neurosci Lett 352:159鈥?62PubMed CrossRef
159.Arnett SV, Alleva LM, Korossy-Horwood R, Clark IA (2011) Chronic fatigue syndrome鈥攁 neuroimmunological model. Med Hypotheses 77:77鈥?3PubMed CrossRef
160.Pall ML (2000) Elevated, sustained peroxynitrite levels as the cause of chronic fatigue syndrome. Med Hypotheses 54:115鈥?25PubMed CrossRef
161.Tanaka M, Ishii A, Watanabe Y (2015) Fatigue in the central nervous system. Austin J Clin Neurol 2:1020
162.Tanaka M, Ishii A, Watanabe Y (2013) Neural dysfunction in chronic fatigue syndrome. Adv Neuroimmune Biol 4:291鈥?00
163.Tanaka M, Ishii A, Watanabe Y (2013) Neural mechanisms underlying chronic fatigue. Rev Neurosci 24:617鈥?28PubMed CrossRef
164.Tanaka M, Watanabe Y (2012) Risk-management syndrome. Int J Psychiatry Clin Pract 16:312鈥?15PubMed CrossRef
165.Tanaka M, Watanabe Y (2010) A new hypothesis of chronic fatigue syndrome: co-conditioning theory. Med Hypotheses 75:244鈥?49PubMed CrossRef
166.Ishii A, Tanaka M, Yamano E, Watanabe Y (2012) Neural substrates activated by viewing others expressing fatigue: a magnetoencephalography study. Brain Res 1455:68鈥?4PubMed CrossRef
167.Wicker B, Keysers C, Plailly J, Royet JP, Gallese V, Rizzolatti G (2003) Both of us disgusted in My insula: the common neural basis of seeing and feeling disgust. Neuron 40:655鈥?64PubMed CrossRef
168.Singer T, Seymour B, O鈥橠oherty J, Kaube H, Dolan RJ, Frith CD (2004) Empathy for pain involves the affective but not sensory components of pain. Science 303:1157鈥?162PubMed CrossRef
169.Botvinick M, Jha AP, Bylsma LM, Fabian SA, Solomon PE, Prkachin KM (2005) Viewing facial expressions of pain engages cortical areas involved in the direct experience of pain. Neuroimage 25:312鈥?19PubMed CrossRef
170.Jabbi M, Swart M, Keysers C (2007) Empathy for positive and negative emotions in the gustatory cortex. Neuroimage 34:1744鈥?753PubMed CrossRef
171.Cheng Y, Yang CY, Lin CP, Lee PL, Decety J (2008) The perception of pain in others suppresses somatosensory oscillations: a magnetoencephalography study. Neuroimage 40:1833鈥?840PubMed CrossRef
172.Fabbri-Destro M, Rizzolatti G (2008) Mirror neurons and mirror systems in monkeys and humans. Physiology (Bethesda) 23:171鈥?79CrossRef
173.Bastiaansen JA, Thioux M, Keysers C (2009) Evidence for mirror systems in emotions. Philos Trans R Soc Lond B Biol Sci 364:2391鈥?404PubMedCentral PubMed CrossRef
174.Johnson SC, Baxter LC, Wilder LS, Pipe JG, Heiserman JE, Prigatano GP (2002) Neural correlates of self-reflection. Brain 125:1808鈥?814PubMed CrossRef
175.Vogt BA, Laureys S (2005) Posterior cingulate, precuneal and retrosplenial cortices: cytology and components of the neural network correlates of consciousness. Prog Brain Res 150:205鈥?17PubMedCentral PubMed CrossRef
176.Vogt BA, Vogt L, Laureys S (2006) Cytology and functionally correlated circuits of human posterior cingulate areas. Neuroimage 29:452鈥?66PubMedCentral PubMed CrossRef
177.Ishii A, Tanaka M, Yamano E, Watanabe Y (2014) The neural substrates of physical fatigue sensation to evaluate ourselves: a magnetoencephalography study. Neuroscience 261:60鈥?7PubMed CrossRef
178.Ishii A, Tanaka M, Watanabe Y (2014) The neural substrates of self-evaluation of mental fatigue: a magnetoencephalography study. PLoS One 9:e95763PubMedCentral PubMed CrossRef
179.Ishii A, Tanaka M, Watanabe Y (2014) The neural mechanisms underlying the decision to rest in the presence of fatigue: a magnetoencephalography study. PLoS One 9:e109740PubMedCentral PubMed CrossRef
180.Otto T, Zijlstra FR, Goebel R (2013) Neural correlates of mental effort evaluation鈥?involvement of structures related to self-awareness. Soc Cogn Affect Neurosci 9:307鈥?15PubMedCentral CrossRef
181.Katafuchi T (2004) Conditioning of fatigue and serotonin system. Mol Med 41:1264鈥?268 (in Japanese)
182.Katafuchi T, Kondo T, Yasaka T, Kubo K, Take S, Yoshimura M (2003) Prolonged effects of polyriboinosinic:polyribocytidylic acid on spontaneous running wheel activity and brain interferon-alpha mRNA in rats: a model for immunologically induced fatigue. Neuroscience 120:837鈥?45PubMed CrossRef
183.Katafuchi T, Kondo T, Take S, Yoshimura M (2005) Enhanced expression of brain interferon-alpha and serotonin transporter in immunologically induced fatigue in rats. Eur J Neurosci 22:2817鈥?826PubMed CrossRef
184.Katafuchi T, Kondo T, Take S, Yoshimura M (2006) Brain cytokines and the 5-HT system during poly I:C-induced fatigue. Ann N Y Acad Sci 1088:230鈥?37PubMed CrossRef
185.Ishii A, Tanaka M, Iwamae M, Kim C, Yamano E, Watanabe Y (2013) Fatigue sensation induced by the sounds associated with mental fatigue and its related neural activities: revealed by magnetoencephalography. Behav Brain Funct 9:24PubMedCentral PubMed CrossRef
186.Tanaka M, Ishii A, Watanabe Y (2013) Neural correlates of central inhibition during physical fatigue. PLoS One 8:e70949PubMedCentral PubMed CrossRef
187.Koyama H, Fukuda S, Shoji T, Inaba M, Tsujimoto Y, Tabata T, Okuno S, Yamakawa T, Okada S, Okamura M, Kuratsune H, Fujii H, Hirayama Y, Watanabe Y, Nishizawa Y (2010) Fatigue is a predictor for cardiovascular outcomes in patients undergoing hemodialysis. Clin J Am Soc Nephrol 5:659鈥?66PubMedCentral PubMed CrossRef
188.Covanis A, Stodieck SR, Wilkins AJ (2004) Treatment of photosensitivity. Epilepsia 45:40鈥?5PubMed CrossRef
189.Uehata T (2005) Nippon Rinsho 63:1249鈥?253 (in Japanese) PubMed - 作者单位：Masaaki Tanaka (1)
Seiki Tajima (2)
Kei Mizuno (3)
Akira Ishii (1)
Yukuo Konishi (2)
Teruhisa Miike (2)
Yasuyoshi Watanabe (1) (3)
1. Department of Physiology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka, 545-8585, Japan
2. Hyogo Children鈥檚 Sleep and Development Medical Research Center, Hyogo Rehabilitation Centre, Central Hospital 1070 Akebono-cho, Nishi-ku, Kobe, Hyogo, 651-2181, Japan
3. RIKEN Center for Life Science Technologies, 6-7-3 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan - 刊物主题：Human Physiology; Neurosciences; Animal Biochemistry; Animal Physiology; Cell Physiology; Neurobiology;
- 出版者：Springer Japan
- ISSN：1880-6562
文摘
Fatigue is defined as a condition or phenomenon of decreased ability and efficiency of mental and/or physical activities, caused by excessive mental or physical activities, diseases, or syndromes. It is often accompanied by a peculiar sense of discomfort, a desire to rest, and reduced motivation, referred to as fatigue sensation. Acute fatigue is a normal condition or phenomenon that disappears after a period of rest; in contrast, chronic fatigue, lasting at least 6 months, does not disappear after ordinary rest. Chronic fatigue impairs activities and contributes to various medical conditions, such as cardiovascular disease, epileptic seizures, and death. In addition, many people complain of chronic fatigue. For example, in Japan, more than one third of the general adult population complains of chronic fatigue. It would thus be of great value to clarify the mechanisms underlying chronic fatigue and to develop efficient treatment methods to overcome it. Here, we review data primarily from behavioral, electrophysiological, and neuroimaging experiments related to neural dysfunction as well as autonomic nervous system, sleep, and circadian rhythm disorders in fatigue. These data provide new perspectives on the mechanisms underlying chronic fatigue and on overcoming it. Keywords Autonomic nervous system Central nervous system Circadian rhythm Fatigue Sleep