A case of lipomatous pseudohypertrophy of the pancreas diagnosed by EUS-FNA

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• 作者：Atsuhiro Masuda (1)
  Hiroshi Tanaka (1)
  Takuya Ikegawa (1)
  Tomokazu Matsuda (2)
  Hideyuki Shiomi (1)
  Mamoru Takenaka (1)
  Nobuyuki Matsuki (1)
  Saori Kakuyama (1)
  Maki Sugimoto (1)
  Tsuyoshi Fujita (1)
  Yoshifumi Arisaka (1)
  Takanobu Hayakumo (1)
  Shigeo Hara (3)
  Takeshi Azuma (1)
  Hiromu Kutsumi (1)
  
• 关键词：Lipomatous pseudohypertrophy of the pancreas ; EUS ; FNA ; Adipose tissue
• 刊名：Clinical Journal of Gastroenterology
• 出版年：2012
• 出版时间：August 2012
• 年：2012
• 卷：5
• 期：4
• 页码：282-286
• 全文大小：889KB
• 参考文献：1. Hantelmann W. Fettsucht und Atrophie der Bauchspecicheldruse bei Jungendlichen. Virchows Arch. 1931;282:630鈥?2. CrossRef
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  3. Izumi S, Nakamura S, Tokumo M, Mano S. A minute pancreatic ductal adenocarcinoma with lipomatous pseudohypertrophy of the pancreas. JOP J Pancreas (Online). 2011;12:464鈥?.
  4. Siegler DIM. Lipomatous pseudohypertrophy of the pancreas associated with chronic pulmonary suppuration in an adult. Postgrad Med J. 1974;50:53鈥?. CrossRef
  5. Nakamura M, Katada N, Sakakibara A, Okumura N, Kato E, Takeichi M, et al. Huge lipomatous pseudohypertrophy of the pancreas. Am J Gastroenterol. 1979;72:171鈥?.
  6. Robson HN, Scott GB. Lipomatous pseudohypertrophy of the pancreas. Gastroenterology. 1953;23:74鈥?1.
  7. Yasuda M, Niina Y, Uchida M, Fujimori N, Nakamura T, Oono T, et al. A case of lipomatous pseudohypertrophy of the pancreas diagnosed by typical imaging. JOP J Pancreas (Online). 2010;11:385鈥?.
  8. Olsen TS. Lipomatosis of the pancreas in autopsy material and its relation to age and overweight. Acta Pathol Microbiol Scand A. 1978;86:367鈥?3.
  9. Shimada M, Shibahara K, Kitamura H, Demura Y, Hada M, Takehara A, et al. Lipomatous pseudohypertrophy of the pancreas taking the form of huge massive lesion of the pancreatic head. Case Rep Gastroenterol. 2010;4:457鈥?4. CrossRef
  
• 作者单位：Atsuhiro Masuda (1)
  Hiroshi Tanaka (1)
  Takuya Ikegawa (1)
  Tomokazu Matsuda (2)
  Hideyuki Shiomi (1)
  Mamoru Takenaka (1)
  Nobuyuki Matsuki (1)
  Saori Kakuyama (1)
  Maki Sugimoto (1)
  Tsuyoshi Fujita (1)
  Yoshifumi Arisaka (1)
  Takanobu Hayakumo (1)
  Shigeo Hara (3)
  Takeshi Azuma (1)
  Hiromu Kutsumi (1)
  
  1. Division of Gastroenterology, Department of Internal Medicine, Graduate School of Medicine, Kobe University, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan
  2. Division of Diabetes, Metabolism, and Endocrinology, Department of Internal Medicine, Graduate School of Medicine, Kobe University, Kobe, Japan
  3. Division of Diagnostic Pathology, Kobe University Graduate School of Medicine, Kobe, Japan
  

文摘

We report the case of a 56-year-old female with lipomatous hypertrophy of the pancreas. Abdominal CT and MRI showed fatty replacement over the entire pancreas. The pancreatic parenchyma was completely absent. ERCP showed no abnormal findings in the main pancreatic duct. EUS-FNA was performed to achieve a definitive diagnosis. Histological features of the FNA specimens revealed that adipose tissue generally replaced the pancreatic parenchyma, and pancreatic acini were identified with a scattered distribution. To consider the differential diagnosis of lipomatous pseudohypertrophy of the pancreas, it is necessary to distinguish it from obesity, diabetes, and age-related pancreatic fat infiltration and liposarcoma. By performing EUS-FNA, it was possible to obtain a definitive diagnosis in this patient. In conclusion, EUS-FNA may be helpful to make a definitive diagnosis in patients with lipomatous hypertrophy of the pancreas.