We describe a relationship between globalizations of local holomorphic actions on Stein manifolds induced by global actions of certain non-compact Lie groups, and holomorphic fiber bundles with smooth Stein base and fiber and connected structure group. To this end we prove a univalence result for particular Stein Riemann domains with a free and properly discontinuous action of a discrete group of biholomorphisms. We then derive some consequences on the existence of Stein globalizations.