Pediatric brain tumors
详细信息    查看全文
  • 作者:Tina Y. Poussaint ; Ashok Panigrahy ; Thierry A. G. M. Huisman
  • 关键词:Brain ; Brain tumor ; Infratentorial ; Magnetic resonance imaging ; Mimics ; Pediatric ; Supratentorial
  • 刊名:Pediatric Radiology
  • 出版年:2015
  • 出版时间:September 2015
  • 年:2015
  • 卷:45
  • 期:3-supp
  • 页码:443-453
  • 全文大小:1,539 KB
  • 参考文献:1.Gurney J, Smith M, Bunin G (1999) CNS and miscellaneous intracranial and intraspinal neoplasms. In: Ries L, Smith M, Gurney J (eds) Cancer incidence and survival among children and adolescents: United States SEER program 1975–1995 NIH publication no. 99–4649. National Cancer Institute SEER Program, Bethesda, pp 51–63
    2.Ostrom QT, Gittleman H, Farah P et al (2013) CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2006–2010. Neuro-Oncol 15:ii1–56
    3.Dunbar SF, Barnes PD, Tarbell NJ (1993) Radiologic determination of the caudal border of the spinal field in cranial spinal irradiation. Int J Radiat Oncol Biol Phys 26:669–673CrossRef PubMed
    4.Gauvain KM, McKinstry RC, Mukherjee P et al (2001) Evaluating pediatric brain tumor cellularity with diffusion-tensor imaging. AJR Am J Roentgenol 177:449–454CrossRef PubMed
    5.Hamstra DA, Rehemtulla A, Ross BD (2007) Diffusion magnetic resonance imaging: a biomarker for treatment response in oncology. J Clin Oncol 25:4104–4109CrossRef PubMed
    6.Qiu D, Kwong DL, Chan GC et al (2007) Diffusion tensor magnetic resonance imaging finding of discrepant fractional anisotropy between the frontal and parietal lobes after whole
    ain irradiation in childhood medulloblastoma survivors: reflection of regional white matter radiosensitivity? Int J Radiat Oncol Biol Phys 69:846–851CrossRef PubMed
    7.Raybaud C, Barkovich AJ (2012) Intracranial, orbital and neck masses of childhood. In: Barkovich AJ, Raybaud C (eds) Pediatric neuroimaging. Lippincott Williams & Wilkins, Philadelphia, pp 637--807
    8.Pollack IF, Jakacki RI (2011) Childhood brain tumors: epidemiology, current management and future directions. Nat Rev Neurol 7:495–506CrossRef PubMed
    9.Taylor MD, Northcott PA, Korshunov A et al (2012) Molecular subgroups of medulloblastoma: the current consensus. Acta Neuropathol 123:465–472PubMedCentral CrossRef PubMed
    10.Maleci A, Cervoni L, Delfini R (1992) Medulloblastoma in children and in adults: a comparative study. Acta Neurochir 119:62–67CrossRef PubMed
    11.Koci TM, Chiang F, Mehringer CM et al (1993) Adult cerebellar medulloblastoma: imaging features with emphasis on MR findings. [see comments]. AJNR Am J Neuroradiol 14:929–939PubMed
    12.Meyers SP, Kemp SS, Tarr RW (1992) MR imaging features of medulloblastomas. AJR Am J Roentgenol 158:859–865CrossRef PubMed
    13.Hayes LL, Jones RA, Palasis S et al (2012) Drop metastases to the pediatric spine revealed with diffusion-weighted MR imaging. Pediatr Radiol 42:1009–1013CrossRef PubMed
    14.Rumboldt Z, Camacho DL, Lake D et al (2006) Apparent diffusion coefficients for differentiation of cerebellar tumors in children. AJNR Am J Neuroradiol 27:1362–1369PubMed
    15.Kovanlikaya A, Panigrahy A, Krieger MD et al (2005) Untreated pediatric primitive neuroectodermal tumor in vivo: quantitation of taurine with MR spectroscopy. Radiology 236:1020–1025CrossRef PubMed
    16.Panigrahy A, Krieger MD, Gonzalez-Gomez I et al (2006) Quantitative short echo time 1H-MR spectroscopy of untreated pediatric brain tumors: preoperative diagnosis and characterization. AJNR Am J Neuroradiol 27:560–572PubMed
    17.Tong Z, Yamaki T, Harada K et al (2004) In vivo quantification of the metabolites in normal brain and brain tumors by proton MR spectroscopy using water as an internal standard. Magn Reson Imaging 22:1017–1024CrossRef PubMed
    18.Perreault S, Ramaswamy V, Achrol AS et al (2014) MRI surrogates for molecular subgroups of medulloblastoma. AJNR Am J Neuroradiol 35:1263–1269CrossRef PubMed
    19.Roujeau T, Machado G, Garnett MR et al (2007) Stereotactic biopsy of diffuse pontine lesions in children. J Neurosurg 107:1–4CrossRef PubMed
    20.Hipp SJ, Steffen-Smith E, Hammoud D et al (2011) Predicting outcome of children with diffuse intrinsic pontine gliomas using multiparametric imaging. Neuro-Oncol 13:904–909PubMedCentral CrossRef PubMed
    21.Prabhu SP, Ng S, Vajapeyam S et al (2011) DTI assessment of the brainstem white matter tracts in pediatric BSG before and after therapy: a report from the pediatric brain tumor consortium. Childs Nerv Syst 27:11–18PubMedCentral CrossRef PubMed
    22.Helton KJ, Edwards M, Steen RG et al (2005) Neuroimaging-detected late transient treatment-induced lesions in pediatric patients with brain tumors. J Neurosurg 102:ii179–186
    23.Poussaint TY, Kocak M, Vajapeyam S et al (2011) MRI as a central component of clinical trials analysis in brainstem glioma: a report from the pediatric brain tumor consortium (PBTC). Neuro-Oncol 13:417–427PubMedCentral CrossRef PubMed
    24.Chen HJ, Panigrahy A, Dhall G et al (2010) Apparent diffusion and fractional anisotropy of diffuse intrinsic brain stem gliomas. AJNR Am J Neuroradiol 31:1879–1885CrossRef PubMed
    25.Helton KJ, Phillips NS, Khan RB et al (2006) Diffusion tensor imaging of tract involvement in children with pontine tumors. AJNR Am J Neuroradiol 27:786–793PubMed
    26.Zukotynski KA, Fahey FH, Kocak M et al (2011) Evaluation of 18 F-FDG PET and MRI associations in pediatric diffuse intrinsic brain stem glioma: a report from the pediatric brain tumor consortium. J Nucl Med 52:188–195PubMedCentral CrossRef PubMed
    27.Panigrahy A, Bluml S (2009) Neuroimaging of pediatric brain tumors: from basic to advanced magnetic resonance imaging (MRI). J Child Neurol 24:1343–1365CrossRef PubMed
    28.Brandão LA, Poussaint TY (2013) Pediatric brain tumors. Neuroimaging Clin N Am 23:499–525CrossRef PubMed
    29.Hwang EI, Packer RJ (2012) Pediatric brain tumors (an overview), vol 2, Pediatric Cancer. Springer, Dordrecht, pp 61–73
    30.Plaza MJ, Borja MJ, Altman N et al (2013) Conventional and advanced MRI features of pediatric intracranial tumors: posterior fossa and suprasellar tumors. AJR Am J Roentgenol 200:1115–1124CrossRef PubMed
    31.Poussaint TY (2008) Diagnostic imaging of primary pediatric brain tumors. In: Hodler J, von Schulthess GK, Zollikofer CL (eds) Diseases of the Brain, Head & Neck, Spine. Springer-Verlag Italia, Milan, pp 277–287
    32.Poussaint TY, Rossi A (2012) Imaging of pediatric brain and spinal cord tumors. In: Hodler J, von Schulthess GK, Zollikofer CL (eds) Diseases of the Brain, Head & Neck, Spine 2012–2015. Springer-Verlag Italia, Milan, pp 203–214
    33.Cavalheiro S, Di Rocco C, Valenzuela S et al (2010) Craniopharyngiomas: intratumoral chemotherapy with interferon-alpha: a multicenter preliminary study with 60 cases. Neurosurg Focus 28:E12–E16
    34.Singh RK, Gutman M, Bucana CD et al (1995) Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas. Proc Natl Acad Sci U S A 92:4562–4566PubMedCentral CrossRef PubMed
    35.Nucci ML, Shorr R, Abuchowski A (1991) The therapeutic value of poly (ethylene glycol)-modified proteins. Adv Drug Deliv Rev 6:133–151CrossRef
    36.Yeung JT, Pollack IF, Panigrahy A et al (2012) Pegylated interferon-alpha-2b for children with recurrent craniopharyngioma. J Neurosurg Pediatr 10:498–503CrossRef PubMed
    37.Jones DT, Kocialkowski S, Liu L et al (2008) Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas. Cancer Res 68:8673–8677PubMedCentral CrossRef PubMed
    38.Pfister S, Janzarik WG, Remke M et al (2008) BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas. J Clin Invest 118:1739–1749PubMedCentral CrossRef PubMed
    39.Raabe EH, Lim KS, Kim JM et al (2011) BRAF activation induces transformation and then senescence in human neural stem cells: a pilocytic astrocytoma model. Clin Cancer Res 17:3590–3599PubMedCentral CrossRef PubMed
    40.Jones DT, Gronych J, Lichter P et al (2012) MAPK pathway activation in pilocytic astrocytoma. Cell Mol Life Sci 69:1799–1811PubMedCentral CrossRef PubMed
    41.Sievert AJ, Lang S-S, Boucher KL et al (2013) Paradoxical activation and RAF inhibitor resistance of BRAF protein kinase fusions characterizing pediatric astrocytomas. Proc Natl Acad Sci 110:5957–5962PubMedCentral CrossRef PubMed
    42.Jones C, Perryman L, Hargrave D (2012) Paediatric and adult malignant glioma: close relatives or distant cousins? Nat Rev Clin Oncol 9:400–413CrossRef PubMed
    43.Fangusaro J (2012) Pediatric high grade glioma: a review and update on tumor clinical characteristics and biology. Front Oncol 2:105 doi:10.​3389/​fonc.​2012.​00105
    44.Suri V, Das P, Jain A et al (2009) Pediatric glioblastomas: a histopathological and molecular genetic study. Neuro-Oncol 11:274–280PubMedCentral CrossRef PubMed
    45.Nakamura M, Shimada K, Ishida E et al (2007) Molecular pathogenesis of pediatric astrocytic tumors. Neuro-Oncol 9:113–123PubMedCentral CrossRef PubMed
    46.Ichimura K, Nishikawa R, Matsutani M (2012) Molecular markers in pediatric neuro-oncology. Neuro-Oncol 14:iv90–99PubMedCentral CrossRef PubMed
    47.Pollack IF, Jakacki RI, Butterfield LH et al (2014) Antigen-specific immune responses and clinical outcome after vaccination with glioma-associated antigen peptides and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in children with newly diagnosed malignant brainstem and nonbrainstem gliomas. J Clin Oncol 32:2050–2058PubMedCentral CrossRef PubMed
    48.Huisman TA (2009) Tumor-like lesions of the brain. Cancer Imaging 9:S10--S13
    49.Lo WD, Lee J, Rusin J et al (2008) Intracranial hemorrhage in children: an evolving spectrum. Arch Neurol 65:1629--1633
    50.McAdam LC, Blaser SI, Banwell BL (2002) Pediatric tumefactive demyelination: case series and review of the literature. Pediatr Neurol 26:18–25CrossRef PubMed
  • 作者单位:Tina Y. Poussaint (1)
    Ashok Panigrahy (2)
    Thierry A. G. M. Huisman (3)

    1. Department of Radiology, 300 Longwood Ave., Boston, MA, 02115, USA
    2. Department of Radiology, Children’s Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    3. Division of Pediatric Radiology and Pediatric Neuroradiology, Charlotte R. Bloomberg Children’s Center, Johns Hopkins Hospital, Baltimore, MD, USA
  • 刊物类别:Medicine
  • 刊物主题:Medicine & Public Health
    Imaging and Radiology
    Pediatrics
    Neuroradiology
    Nuclear Medicine
    Ultrasound
    Oncology
  • 出版者:Springer Berlin / Heidelberg
  • ISSN:1432-1998
文摘
Among all causes of death in children from solid tumors, pediatric brain tumors are the most common. This article includes an overview of a subset of infratentorial and supratentorial tumors with a focus on tumor imaging features and molecular advances and treatments of these tumors. Key to understanding the imaging features of brain tumors is a firm grasp of other disease processes that can mimic tumor on imaging. We also review imaging features of a common subset of tumor mimics.

© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号

地址:北京市海淀区学院路29号 邮编:100083

电话:办公室:(+86 10)66554848;文献借阅、咨询服务、科技查新:66554700