DocOx (AIO-PK0106): a phase II trial of docetaxel and oxaliplatin as a second line systemic therapy in patients with advanced pancreatic ductal adenocarcinoma

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• 作者：Thomas J. Ettrich ; Lukas Perkhofer ; Goetz von Wichert ; Thomas M. Gress…
• 关键词：Pancreatic cancer ; Advanced disease ; Second line therapy
• 刊名：BMC Cancer
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：16
• 期：1
• 全文大小：748 KB
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• 作者单位：Thomas J. Ettrich
  Lukas Perkhofer
  Goetz von Wichert (2)
  Thomas M. Gress (3)
  Patrick Michl (4)
  Holger F. Hebart (5)
  Petra Büchner-Steudel (4)
  Michael Geissler (6)
  Rainer Muche (7)
  Bettina Danner (7)
  Volker Kächele (8)
  Andreas W. Berger (1)
  Melanie Güthle (1)
  Thomas Seufferlein (1)
  
  2. Department of Internal Medicine, Schön-Klinik Hamburg-Eilbeck, Hamburg, Germany
  3. Department of Gastroenterology, Endocrinology, Metabolism and Infectiology, Philipps University of Marburg, Marburg, Germany
  4. Department of Internal Medicine I, Martin-Luther-University, Halle (Saale), Germany
  5. Department of Internal Medicine, Stauferklinikum Schwaebisch-Gmuend, Mutlangen, Germany
  6. Department of Internal Medicine, Oncology/Hematology, Gastroenterology, Esslingen Hospital, Esslingen, Germany
  7. Institute of Epidemiology and Medical Biometry, Ulm University, Ulm, Germany
  8. Praxis für Hämatologie und Onkologie Ulm, Ulm, Germany
  1. Department of Internal Medicine I, Ulm University, Albert-Einstein-Allee 23, D-89081, Ulm, Germany
  
• 刊物主题：Cancer Research; Oncology; Stem Cells; Animal Models; Internal Medicine;
• 出版者：BioMed Central
• ISSN：1471-2407

文摘

Background The current study was conducted to examine the activity of a docetaxel/oxaliplatin (DocOx) combination as second line treatment for advanced pancreatic ductal adenocarcinoma (Trial registration: NCT00690300. Registered June 2, 2008)