The 2011-016 Transdisciplinary Research on Energetics and Cancer (TREC) Initiative: Rationale and Design
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- 作者：Ruth E. Patterson (1)
Graham A. Colditz (2)
Frank B. Hu (3)
Kathryn H. Schmitz (4)
Rexford S. Ahima (4)
Ross C. Brownson (2)
Kenneth R. Carson (2)
Jorge E. Chavarro (3)
Lewis A. Chodosh (4)
Sarah Gehlert (2)
Jeff Gill (2)
Karen Glanz (4)
Debra Haire-Joshu (2)
Karen Louise Herbst (1)
Christine M. Hoehner (2)
Peter S. Hovmand (2)
Melinda L. Irwin (5)
Linda A. Jacobs (4)
Aimee S. James (2)
Lee W. Jones (6)
Jacqueline Kerr (1)
Adam S. Kibel (3)
Irena B. King (7)
Jennifer A. Ligibel (8)
Jeffrey A. Meyerhardt (8)
Loki Natarajan (1)
Marian L. Neuhouser (9)
Jerrold M. Olefsky (1)
Enola K. Proctor (2)
Susan Redline (10)
Cheryl L. Rock (1)
Bernard Rosner (11)
David B. Sarwer (4)
J. Sanford Schwartz (4)
Dorothy D. Sears (1)
Howard D. Sesso (10)
Meir J. Stampfer (3)
S. V. Subramanian (3)
Elsie M. Taveras (12)
Julia Tchou (4)
Beti Thompson (9)
Andrea B. Troxel (4)
Marianne Wessling-Resnick (3)
Kathleen Y. Wolin (2)
Mark D. Thornquist (9) - 关键词：Energetics ; Obesity ; Diet ; Physical activity ; Cancer ; Transdisciplinary
- 刊名：Cancer Causes and Control
- 出版年：2013
- 出版时间：April 2013
- 年：2013
- 卷：24
- 期：4
- 页码：695-704
- 全文大小：304KB
- 参考文献：1. Flegal KM, Carroll MD, Kit BK, Ogden CL (2012) Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-010. JAMA 307:91-7 CrossRef
2. Ogden CL, Carroll MD, Kit BK, Flegal KM (2012) Prevalence of obesity and trends in the distribution of body mass index among US children and adolescents. JAMA 307:83-0 CrossRef
3. Finkelstein EA, Trogdon JG, Cohen JW, Dietz W (2009) Annual medical spending attributable to obesity: payer-and service-specific estimates. Health Aff (Millwood) 28(5):w822–w831 CrossRef
4. Basen-Engquist K, Chang M (2011) Obesity and cancer risk: recent review and evidence. Curr Oncol Rep 13:71-6 CrossRef
5. Wolin KY, Carson K, Colditz GA (2010) Obesity and cancer. Oncologist 15:556-65 CrossRef
6. Pan SY, DesMeules M (2009) Energy intake, physical activity, energy balance, and cancer: epidemiologic evidence. Methods Mol Biol 472:191-15 CrossRef
7. Bianchini F, Kaaks R, Vainio H (2002) Overweight, obesity, and cancer risk. Lancet Oncol 3:565-74 CrossRef
8. Winzer BM, Whiteman DC, Reeves MM, Paratz JD (2011) Physical activity and cancer prevention: a systematic review of clinical trials. Cancer Causes Control 22:811-26 CrossRef
9. Davies NJ, Batehup L, Thomas R (2011) The role of diet and physical activity in breast, colorectal, and prostate cancer survivorship: a review of the literature. Br J Cancer 1:S52–S73 CrossRef
10. Friedenreich CM, Neilson HK, Lynch BM (2010) State of the epidemiological evidence on physical activity and cancer prevention. Eur J Cancer 46:2593-604 CrossRef
11. Ballard-Barbash R, Hunsberger S, Alciati MH et al (2009) Physical activity, weight control, and breast cancer risk and survival: clinical trial rationale and design considerations. J Natl Cancer Inst 101:630-43 CrossRef
12. Speck RM, Courneya KS, Masse LC, Duval S, Schmitz KH (2010) An update of controlled physical activity trials in cancer survivors: a systematic review and meta-analysis. J Cancer Surv 4:87-00 CrossRef
13. Patterson RE, Cadmus LA, Emond JA, Pierce JP (2010) Physical activity, diet, adiposity and breast cancer prognosis: a review of the epidemiologic literature. Maturitas 66:5-5 CrossRef
14. Schmitz KH, Courneya KS, Matthews C et al (2010) American college of sports medicine roundtable on exercise guidelines for cancer survivors. Med Sci Sports Exerc 42:1409-426 CrossRef
15. Jones LW, Demark-Wahnefried W (2006) Diet, exercise, and complementary therapies after primary treatment for cancer. Lancet Oncol 7:1017-026 CrossRef
16. Hewitt M, Greenfield S, Stovall E (2006) From cancer patient to cancer survivor: lost in transition. The National Academies Press, Washington
17. Harvey AE, Lashinger LM, Hursting SD (2011) The growing challenge of obesity and cancer: an inflammatory issue. Ann NY Acad Sci 1229:45-2 CrossRef
18. Gallagher EJ, Fierz Y, Ferguson RD, LeRoith D (2010) The pathway from diabetes and obesity to cancer, on the route to targeted therapy. Endocr Pract 16:864-73 CrossRef
19. Roberts DL, Dive C, Renehan AG (2010) Biological mechanisms linking obesity and cancer risk: new perspectives. Annu Rev Med 61:301-16 CrossRef
20. Tsugane S, Inoue M (2010) Insulin resistance and cancer: epidemiological evidence. Cancer Sci 101:1073-079 CrossRef
21. Lynch BM, Neilson HK, Friedenreich CM (2011) Physical activity and breast cancer prevention. Recent Results Cancer Res 186:13-2 CrossRef
22. Stokols D, Hall KL, Taylor BK, Moser RP (2008) The science of team science. Overview of the field and introduction to the supplement. Am J Prev Med 35:S77–S89 CrossRef
23. Croyle RT (2008) The National Cancer Institute’s transdisciplinary centers initiatives and the need for building a science of team science. Am J Prev Med 35:S90–S93 CrossRef
24. Warnecke RB, Oh A, Breen N, Gehlert S, Paskett E, Tucker KL, Lurie N, Rebbeck T, Goodwin J, Flack J, Srinivasan S, Kerner J, Heurtin-Roberts S, Abeles R, Tyson FL, Patmios G, Hiatt RA (2008) Approaching health disparities from a population perspective: the National Institutes of Health Centers for population health and health disparities. Am J Public Health 98(9):1608-615 CrossRef
25. Abrams DB, Leslie F, Mermelstein R, Kobus K, Clayton RR (2003) Transdisciplinary tobacco use research. Nicotine Tob Res 5(Suppl 1):S5–S10 CrossRef
26. Hall KL, Stokols D, Stipelman BA, Vogel AL, Feng A, Masimore B, Morgan G, Moser RP, Marcus SE, Berrigan D (2012) Assessing the value of team science: a study comparing center- and investigator-initiated grants. Am J Prev Med 42(2):157-63 CrossRef
27. Rimer BK, Abrams DB (2012) Present and future horizons for transdisciplinary research. Am J Prev Med 42(2):200-01 CrossRef
28. Vogel AL, Feng A, Oh A, Hall KL, Stipelman B, Okamoto J, Stokols D, Moser RP, Perna F, Nebeling L (2012) Influences of a National Cancer Institute transdisciplinary research and training initiative on trainees-transdisciplinary research competencies and scholarly productivity. Transl Behav Med 4(2):459-68
29. Stokols D, Hall KL, Vogel AL (2012) Transdisciplinary public health: definitions, core characteristics, and strategies for success. In: Haire-Joshu D, McBride TD (eds) Transdisciplinary public health: research, methods, and practice. Jossey-Bass, San Francisco
30. Hall KL, Stokols D, Moser RP et al (2008) The collaborative readiness of transdisciplinary research teams and centers. Findings from the National Cancer Institute’s TREC year-one evaluation study. Am J Prev Med 35:S161–S172 CrossRef
31. Neuhouser ML, Schwartz Y, Wang C, Breymeyer K, Coronado G, Wang CY, Noar K, Song X, Lampe JW (2012) A low-glycemic load diet reduces serum C-reactive protein and modestly increases adiponectin in overweight and obese adults. J Nutr 142(2):369-74 CrossRef
32. Behan JW, Yun JP, Proektor MP, Ehsanipour EA, Arutyunyan A, Moses AS, Avramis VI, Louie SG, Butturini A, Heisterkamp N, Mittelman SD (2009) Adipocytes impair leukemia treatment in mice. Cancer Res 19:7867-874 CrossRef
33. Campbell PT, Gross MD, Potter JD, Schmitz KH, Duggan C, McTiernan A, Ulrich CM (2010) Effect of exercise on oxidative stress: a 12-month randomized, controlled trial. Med Sci Sports Exerc 42(8):1448-453 CrossRef
34. Thompson CL, Larkin EK, Patel S, Berger NA, Redline S, Li L (2011) Short duration of sleep increases risk of colorectal adenoma. Cancer 117(4):841-47 CrossRef
35. Arikawa AY, O’Dougherty M, Kaufman B, Thomas W, Warren M, Kurzer M, Schmitz KH (2010) Women in steady exercise research (WISER): study design and methods. Contemp Clin Trials 31:457-65 CrossRef
36. Arikawa AY, Kurzer MS, Thomas W, Schmitz KH (2010) No effect of exercise on insulin-like growth factor (IGF)-1, insulin and glucose in young women participating in a 16-week randomized controlled trial. Cancer Epidemiol Biomark Prev 19:2987-990 CrossRef
37. Arikawa AY, Thomas W, Schmitz KH, Kurzer MS (2011) Sixteen weeks of exercise reduces C-reactive protein levels in young women. Med Sci Sports Exerc 43:1002-009 CrossRef
38. Smith AJ, Phipps WR, Arikawa AY, O’Dougherty M, Kaufman B, Thomas W, Schmitz KH, Kurzer MS (2011) Effects of aerobic exercise on premenopausal sex hormone levels: results of the WISER study, a randomized clinical trial in healthy, sedentary, eumenorrheic women. Cancer Epidemiol Biomark Prev 20:1098-106 CrossRef
39. Schmitz KH, Ahmed RL, Troxel A, Cheville A, Smith R, Grant LL, Bryan CJ, Williams-Smith CT, Greene QP (2009) Weight lifting in women with breast cancer-related lymphedema. New Engl J Med 361:664-73 CrossRef
40. Schmitz KH, Ahmed RL, Troxel AB, Cheville A, Lewis-Grant L, Smith R, Bryan CJ, Williams-Smith CT, Chittams J (2010) Weight-lifting for women at risk for breast cancer-related lymphedema: a randomized trial. JAMA 304:2699-705 CrossRef - 作者单位：Ruth E. Patterson (1)
Graham A. Colditz (2)
Frank B. Hu (3)
Kathryn H. Schmitz (4)
Rexford S. Ahima (4)
Ross C. Brownson (2)
Kenneth R. Carson (2)
Jorge E. Chavarro (3)
Lewis A. Chodosh (4)
Sarah Gehlert (2)
Jeff Gill (2)
Karen Glanz (4)
Debra Haire-Joshu (2)
Karen Louise Herbst (1)
Christine M. Hoehner (2)
Peter S. Hovmand (2)
Melinda L. Irwin (5)
Linda A. Jacobs (4)
Aimee S. James (2)
Lee W. Jones (6)
Jacqueline Kerr (1)
Adam S. Kibel (3)
Irena B. King (7)
Jennifer A. Ligibel (8)
Jeffrey A. Meyerhardt (8)
Loki Natarajan (1)
Marian L. Neuhouser (9)
Jerrold M. Olefsky (1)
Enola K. Proctor (2)
Susan Redline (10)
Cheryl L. Rock (1)
Bernard Rosner (11)
David B. Sarwer (4)
J. Sanford Schwartz (4)
Dorothy D. Sears (1)
Howard D. Sesso (10)
Meir J. Stampfer (3)
S. V. Subramanian (3)
Elsie M. Taveras (12)
Julia Tchou (4)
Beti Thompson (9)
Andrea B. Troxel (4)
Marianne Wessling-Resnick (3)
Kathleen Y. Wolin (2)
Mark D. Thornquist (9)
1. University of California, San Diego, La Jolla, CA, USA
2. Washington University in St. Louis, St. Louis, MO, USA
3. Harvard University, Boston, MA, USA
4. University of Pennsylvania, Philadelphia, PA, USA
5. Yale University, New Haven, CT, USA
6. Duke Cancer Institute, Durham, NC, USA
7. University of New Mexico, Albuquerque, NM, USA
8. Dana-Farber Cancer Institute, Boston, MA, USA
9. Fred Hutchinson Cancer Research Center, Seattle, WA, USA
10. Brigham and Women’s Hospital, Boston, MA, USA
11. Channing Laboratory, Boston, MA, USA
12. Harvard Pilgrim Health Care Institute, Boston, MA, USA - ISSN：1573-7225
文摘
Purpose Recognition of the complex, multidimensional relationship between excess adiposity and cancer control outcomes has motivated the scientific community to seek new research models and paradigms. Methods The National Cancer Institute developed an innovative concept to establish a center grant mechanism in nutrition, energetics, and physical activity, referred to as the Transdisciplinary Research on Energetics and Cancer (TREC) Initiative. This paper gives an overview of the 2011-016 TREC Collaborative Network and the 15 research projects being conducted at the centers. Results Four academic institutions were awarded TREC center grants in 2011: Harvard University, University of California San Diego, University of Pennsylvania, and Washington University in St. Louis. The Fred Hutchinson Cancer Research Center is the Coordination Center. The TREC research portfolio includes three animal studies, three cohort studies, four randomized clinical trials, one cross-sectional study, and two modeling studies. Disciplines represented by TREC investigators include basic science, endocrinology, epidemiology, biostatistics, behavior, medicine, nutrition, physical activity, genetics, engineering, health economics, and computer science. Approximately 41,000 participants will be involved in these studies, including children, healthy adults, and breast and prostate cancer survivors. Outcomes include biomarkers of cancer risk, changes in weight and physical activity, persistent adverse treatment effects (e.g., lymphedema, urinary and sexual function), and breast and prostate cancer mortality. Conclusion The NIH Science of Team Science group will evaluate the value added by this collaborative science. However, the most important outcome will be whether this transdisciplinary initiative improves the health of Americans at risk of cancer as well as cancer survivors.