Percutaneous implantation of 125iodine seeds for treatment of portal vein tumor thrombosis in hepatocellular carcinoma

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• 作者：Yan Liu ; Ruibao Liu ; Ping Wang ; Shijie Li ; Haiyang Shen
• 关键词：Hepatocellular carcinoma ; Portal vein tumor thrombosis ; 125I seed
• 刊名：Medical Oncology
• 出版年：2015
• 出版时间：August 2015
• 年：2015
• 卷：32
• 期：8
• 全文大小：438 KB
• 参考文献：1.Wallace MC, Preen D, Jeffrey GP, Adams LA. The evolving epidemiology of hepatocellular carcinoma: a global perspective. Expert Rev Gastroenterol Hepatol. 2015;9(6):765-9. doi:10.-586/-7474124.-015.-028363 .PubMed
  2.Tanaka K, Shimada M, Kudo M. Characteristics of long-term survivors following sorafenib treatment for advanced hepatocellular carcinoma: report of a workshop at the 50th Annual Meeting of the Liver Cancer Study Group of Japan. Oncology. 2014;87(Suppl 1):104-. doi:10.-159/-00368153 .PubMed View Article
  3.Raza A, Sood GK. Hepatocellular carcinoma review: current treatment, and evidence-based medicine. World J Gastroenterol WJG. 2014;20(15):4115-7. doi:10.-748/?wjg.?v20.?i15.-115 .PubMed View Article
  4.Graf D, Vallbohmer D, Knoefel WT, Kropil P, Antoch G, Sagir A, et al. Multimodal treatment of hepatocellular carcinoma. Eur J Intern Med. 2014;25(5):430-. doi:10.-016/?j.?ejim.-014.-3.-01 .PubMed View Article
  5.Lau WY, Lai EC. Hepatocellular carcinoma: current management and recent advances. Hepatobiliary Pancreat Dis Int HBPD INT. 2008;7(3):237-7.PubMed
  6.Llovet JM, Bruix J. Prospective validation of the Cancer of the Liver Italian Program (CLIP) score: a new prognostic system for patients with cirrhosis and hepatocellular carcinoma. Hepatology. 2000;32(3):679-0. doi:10.-053/?jhep.-000.-6475 .PubMed View Article
  7.Park KW, Park JW, Choi JI, Kim TH, Kim SH, Park HS, et al. Survival analysis of 904 patients with hepatocellular carcinoma in a hepatitis B virus-endemic area. J Gastroenterol Hepatol. 2008;23(3):467-3. doi:10.-111/?j.-440-1746.-007.-5112.?x .PubMed View Article
  8.Villa E, Moles A, Ferretti I, Buttafoco P, Grottola A, Del Buono M, et al. Natural history of inoperable hepatocellular carcinoma: estrogen receptors-status in the tumor is the strongest prognostic factor for survival. Hepatology. 2000;32(2):233-. doi:10.-053/?jhep.-000.-603 .PubMed View Article
  9.Minagawa M, Makuuchi M. Treatment of hepatocellular carcinoma accompanied by portal vein tumor thrombus. World J Gastroenterol WJG. 2006;12(47):7561-.PubMed
  10.Parashar B, Arora S, Wernicke AG. Radiation therapy for early stage lung cancer. Semin Intervent Radiol. 2013;30(2):185-0. doi:10.-055/?s-0033-1342960 .PubMed Central PubMed View Article
  11.Li W, Guan J, Yang L, Zheng X, Yu Y, Jiang J. Iodine-125 brachytherapy improved overall survival of patients with inoperable stage III/IV non-small cell lung cancer versus the conventional radiotherapy. Med Oncol. 2015;32(1):1-.View Article
  12.Stannard C, Maree G, Tovey S, Hunter A, Wetter J. Iodine-125 brachytherapy in the management of squamous cell carcinoma of the oral cavity and oropharynx. Brachytherapy. 2014;13(4):405-2. doi:10.-016/?j.?brachy.-014.-2.-43 .PubMed View Article
  13.Huang MW, Liu SM, Zheng L, Shi Y, Zhang J, Li YS, et al. A digital model individual template and CT-guided 125I seed implants for malignant tumors of the head and neck. J Radiat Res. 2012;53(6):973-. doi:10.-093/?jrr/?rrs046 .PubMed Central PubMed View Article
  14.Korinthenberg R, Neuburger D, Nikkhah G, Teske C, Schnabel K, Calaminus G. Assessing quality of life in long-term survivors after (1)(2)(5)I brachytherapy for low-grade glioma in childhood. Neuropediatrics. 2011;42(3):110-. doi:10.-055/?s-0031-1283111 .PubMed View Article
  15.Rombouts SJ, Vogel JA, van Santvoort HC, van Lienden KP, van Hillegersberg R, Busch OR, et al. Systematic review of innovative ablative therapies for the treatment of locally advanced pancreatic cancer. Br J Surg. 2015;102(3):182-3. doi:10.-002/?bjs.-716 .PubMed View Article
  16.Nickers P, Thissen B, Jansen N, Deneufbourg JM. 192Ir or 125I prostate brachytherapy as a boost to external beam radiotherapy in locally advanced prostatic cancer: a dosimetric point of view. Radiother Oncol J Eur Soc Ther Radiol Oncol. 2006;78(1):47-2. doi:10.-016/?j.?radonc.-005.-9.-02 .View Article
  17.Perez BA, Mettu P, Vajzovic L, Rivera D, Alkaissi A, Steffey BA, et al. Uveal melanoma treated with iodine-125 episcleral plaque: an analysis of dose on disease control and visual outcomes. Int J Radiat Oncol Biol Phys. 2014;89(1):127-6. doi:10.-016/?j.?ijrobp.-014.-1.-26 .PubMed Central PubMed View Article
  18.Shah NV, Houston SK, Markoe A, Murray TG. Combination therapy with triamcinolone acetonide and bevacizumab for the treatment of severe radiation maculopathy in patients with posterior uveal melanoma. Clin Ophthalmol. 2013;7:1877-2. doi:10.-147/?OPTH.?S47684 .PubMed Central PubMed
  19.Shields CL, Shah SU, Bianciotto CG, Emrich J, Komarnicky L, Shields JA. Iris melanoma management with iodine-125 plaque radiotherapy in 144 patients: impact of melanoma-related glaucoma on outcomes. Ophthalmology. 2013;120(1):55-1. doi:10.-016/?j.?ophtha.-012.-6.-53 .PubMed View Article
  20.Gao F, Li C, Gu Y, Huang J, Wu P. CT-guided 125I brachytherapy for mediastinal metastatic lymph no
• 作者单位：Yan Liu (1)
  Ruibao Liu (1)
  Ping Wang (1)
  Shijie Li (1)
  Haiyang Shen (1)
  
  1. Department of Interventional Radiology, The Tumor Hospital of Harbin Medical University, Harbin, 150040, China
  
• 刊物主题：Oncology; Hematology; Pathology; Internal Medicine;
• 出版者：Springer US
• ISSN：1559-131X

文摘

The aim of the study is to evaluate the practicability and therapeutic efficacy of 125iodine seeds implantation percutaneously for portal vein tumor thrombosis (PVTT) in patients with hepatocellular carcinoma (HCC). Nineteen patients with HCC accompanied with PVTT received ultrasound-guided implantation of 8-0 125iodine seeds, 8?mm apart within the portal vein tumor thrombi. The patients were followed up postoperatively for a period of 3-2?months. The successful rates of the procedure, postoperative changes of liver and renal function, hemogram, complications and therapeutic response were monitored. 125I seeds were successfully implanted in the portal veins in all patients without serious complications. During the follow-up period, the portal vein tumor thrombi all shrunk obviously. Percutaneous implantation of 125iodine seeds into the portal vein is an effective and safe treatment for PVTT accompanying HCC.