The changes in the hemodynamic activity of the brain during motor imagery training with the use of brain-computer interface

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• 作者：A. A. Frolov ; D. Husek ; A. V. Silchenko ; J. Tintera ; J. Rydlo
• 关键词：brain ; computer interface ; motor imagery ; hemodynamic activity ; brain plasticity ; functional MRI
• 刊名：Human Physiology
• 出版年：2016
• 出版时间：January 2016
• 年：2016
• 卷：42
• 期：1
• 页码：1-12
• 全文大小：635 KB
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• 作者单位：A. A. Frolov (1) (2) (3)
  D. Husek (4)
  A. V. Silchenko (1) (3) (6)
  J. Tintera (5)
  J. Rydlo (5)
  
  1. Institute for Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, ul. Butlerova 5a, Moscow, 117865, Russia
  2. Pirogov Russian National Research Medical University, ul. Ostrovityanova 1, Moscow, 117997, Russia
  3. Technical University of Ostrava, 17 Listopadu 2172/15, 708 00, Ostrava-Poruba, Czech Republic
  4. Institute of Computer Science, Academy of Sciences of the Czech Republic, Radlicka 5, Prague 5, 158 00, Czech Republic
  6. Faculty of Physics, Moscow State University, Moscow, 119991, Russia
  5. Institute for Clinical and Experimental Medicine (IKEM), Prague, Czech Republic
  
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Life Sciences
  Life Sciences
  Human Physiology
  Biomedicine
  Russian Library of Science
  
• 出版者：MAIK Nauka/Interperiodica distributed exclusively by Springer Science+Business Media LLC.
• ISSN：1608-3164

文摘

With the use of functional MRI (fMRI), we studied the changes in brain hemodynamic activity of healthy subjects during motor imagery training with the use brain-computer interface (BCI), which is based on the recognition of EEG patterns of imagined movements. ANOVA dispersion analysis showed there are 14 areas of the brain where statistically significant changes were registered. Detailed analysis of the activity in these areas before and after training (Student’s and Mann-Whitney tests) showed that the real amount of such areas is five; these are Brodmann areas 44 and 45, insula, middle frontal gyrus and anterior cingulate gyrus. We suggest that these changed are caused by the formation of memory traces of those brain activity patterns which are most accurately recognized by BCI classifiers as correspondent with limb movements imagery. We also observed a tendency of increase in the activity of motor imagery after training. The hemodynamic activity in all these 14 areas during real movements was either approximately the same or significantly higher than during motor imagery; activity during imagined leg movements was higher than that during imagines arm movements, except for the areas of representation of arms.