Synthesis and bio-evaluation of novel 7-hydroxy coumarin derivatives via Knoevenagel reaction
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  • 作者:Mark Manidhar Darla (1)
    Balam Sateesh Krishna (1)
    K. Umamaheswara Rao (1)
    N. Baktavathsala Reddy (1)
    Manoj Kumar Srivash (3)
    K. Adeppa (3)
    Ch. Syama Sundar (1)
    Cirandur Suresh Reddy (1)
    Krishna Misra (2)

    1. Department of Chemistry
    ; Sri Venkateswara University ; Tirupati ; India
    3. R&D Centre
    ; India Pesticides Limited ; Lucknow ; 226004 ; India
    2. Indian Institute of Information Technology
    ; Jhalwa Campus ; Allahabad ; India
  • 关键词:Cyano acetamide derivatives ; Knoevenagel reaction ; Fluconazole ; Aspergillus niger ; Candida albicans ; Escherichia coli ; Staphylococcus aureus ; Pseudomonas aeruginosa ; Norfloxacin
  • 刊名:Research on Chemical Intermediates
  • 出版年:2015
  • 出版时间:February 2015
  • 年:2015
  • 卷:41
  • 期:2
  • 页码:1115-1133
  • 全文大小:3,032 KB
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    5. N. Nida, M.R. Farshori, A.A. Banday, U.K. Asad, A. Rauf, 7-Hydroxy-coumarin derivatives: synthesis, characterization and preliminary antimicrobial activities. Med. Chem. Res. 20(5), 535鈥?41 (2011) CrossRef
    6. Z.M. Nofal, M.I. El-Zahar, S.S. Abd El-Karim, Novel coumarin derivatives with expected biological activity. Molecules 5, 99鈥?13 (2000) CrossRef
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    8. T. Suvit, N.M. Janakiraman, Structure-based design of novel HIV protease inhibitors: sulfonamide-Containing 4-Hydroxycoumarins and 4-Hydroxy-2-pyrones as Potent Non-Peptidic Inhibitors. J. Med. Chem. 39, 2400鈥?410 (1996) CrossRef
    9. S.S. Bhattacharyya, P. Saili, S.K. Mandal, A.B. Naoual, A.R. Khuda-Bukhsh, A synthetic coumarin (4-methyl-7-hydroxy coumarin) has anticancer potentials against DMBA-induced skin cancer in mice. Eur. J. Pharmacolozy 614, 128鈥?36 (2009) CrossRef
    10. G. Aviv, O. Nir, P. Israel, Y. Pnina, Heterocyclic and alfa substituted Tyrphostins as inhibitors. J. Med. Chem. 34, 1896鈥?907 (1991) CrossRef
    11. T.S. Osdene, A. Arthur, E.L. Mc Cardle, M.E. Rosenthale, Pteridine carboxamide diuretics. II. Reaction of 1,6-Diamino-5-nitropyridines with N-substituted cyanoacetamides. J. Med. Chem. 10, 165鈥?71 (1967)
    12. E. Knoevenagel, Conensation between malonic esters and aldehydes under the influence of ammonia and organic amines. Berichte der deutschen chemischen Gesellschaft, Knoevenagel condensation. Berichte. 31, 2585鈥?596 (1898)
    13. S. Fioravanti, L. Pellacani, P.A. Tardella, M.C. Vergari, Facile and highly stereoselective one-pot synthesis of either (E).or (Z)-Nitro Alkenes. Org. Lett. 10, 1449鈥?451 (2008) CrossRef
    14. V. Bobbarala, P.K. Katikala, K.C. Naidu, S. Penumajji, Antifungal activity of selected plant extracts against phytopathogenic fungi Aspergillus niger F 2723. Indian. J. Sci. Technol. 2(4), 87鈥?0 (2009)
    15. H.V. Pechmann, C. Duisberg, Synthesis of coumarins by condensation of phenols with beta keto ester in presence of Lewis acid catalysts. Berichte 16, 2119 (1893)
    16. A.D. Patel, S.M. Sangita, J.J. Vohra, J.D. Joshi, Synthesis, characterization and antimicrobial activities of Binary and ternary Complex of UO2II and ThIV Complex with 5-hydroxymethyl-8-quinolinol and 8-formyl-7-hydroxy-4-methyl-2H-1-benzopyran-2-one with Aniline. J. Indian Chem. Soc. 74, 287鈥?88 (1997)
    17. B. Michael, Jig Cadogan, Hamish Mc Nab, A.D. Mac Pherson, C. Smith, V. Peter Roddam, Carol Smith, R.S. Helen, Synthesis of fused furans by gas phase Pyrolysis of 2-allyoxyaryl 2-one with aniline. J. Chem. Soc. Perkin Trans 1, 2483鈥?493 (1997)
    18. K. Wang, K. Nguyen, Y. Huang, A. Domling, Cyanoacetamide multicomponent reaction (I): parallel synthesis of cyanoacetamides. J. Comb. Chem. 11, 920鈥?27 (2009) CrossRef
    19. A.P. Tamiz, S.X. Cai, Z.L. Zhou, P.W. Yuen, R.M. Schelkun, E.R. Whittemore, E. Weber, R.M. Woodward, J.F. Keana, Structure activity relationship of N-(phenylalkyl)cinnamides as novel NR2B subtype-selective NMDA receptor antagonists. J. Med. Chem. 42, 3412鈥?420 (1999) CrossRef
    20. K.E. Price, C.L. Aboussafy, B.M. Lillie, R.W. McLaughlin, J. Mustakis, K.W. Hettenbach, J.M. Hawkins, R. Vaidyanalhan,聽Mild and efficient DBU-catalysed amidation of cyanoacetates. Org. Lett. 1(9), 2003鈥?006 (2009)
    21. A. Mc Chuskey, P.J. Robinson, T. Hill, J.L. Scott, J.K. Edwards, Green chemistry approaches to the Knoevenagel condensation : comparison of Ethanol, water and solvent free(dry grind) approaches. Tetrahedron Lett. 43, 3117鈥?120 (2002)
  • 刊物类别:Chemistry and Materials Science
  • 刊物主题:Chemistry
    Catalysis
    Physical Chemistry
    Inorganic Chemistry
  • 出版者:Springer Netherlands
  • ISSN:1568-5675
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