The presence and impact of estrogen metabolism on the biology of triple-negative breast cancer
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- 作者：Keely May McNamara ; Saki Oguro ; Fumiya Omata…
- 关键词：TNBC ; Estrogens ; Estrogen receptor beta ; Steroid metabolism ; Androgens ; Breast cancer
- 刊名：Breast Cancer Research and Treatment
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：161
- 期：2
- 页码：213-227
- 全文大小：
- 刊物类别：Medicine
- 刊物主题：Oncology;
- 出版者：Springer US
- ISSN：1573-7217
- 卷排序：161
文摘
PurposeWhile triple-negative breast cancer (TNBC) is negative for estrogen receptor alpha, a substantial proportion of carcinomas express estrogen receptor beta (ERβ); consequently, estrogen actions and metabolism may be relevant in this cancer subtype.