Sulfonylurea Poisoning in a Healthy Toddler

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• 作者：Suresh Kumar ; Abhijit Choudhary ; Mahammad Ali…
• 关键词：Hypoglycemia ; Sulfonylurea ; Dextrose ; Octreotide
• 刊名：The Indian Journal of Pediatrics
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：84
• 期：2
• 页码：147-149
• 全文大小：
• 刊物主题：Pediatrics; Gynecology;
• 出版者：Springer India
• ISSN：0973-7693
• 卷排序：84

文摘

Ingestion of sulfonylureas is life-threatening in toddlers and children due to its strong and prolonged hypoglycemic effect. The authors present a 15-mo-old boy with accidental ingestion of Glipizide who presented with encephalopathy, seizure and severe hypoglycemia. The management included parenteral dextrose and octreotide administration to maintain euglycemia, followed by complete neurological recovery within 24 h. Sulphonylurea intoxication should be considered in previously healthy toddlers and children presenting with hypoglycemia especially if any caregiver is on sulfonylurea drugs.