Accurate prediction of protein relative solvent accessibility using a balanced model
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- 作者：Wei Wu ; Zhiheng Wang ; Peisheng Cong ; Tonghua Li
- 关键词：Balanceable model ; Prediction ; Profile ; Relative solvent accessibility
- 刊名：BioData Mining
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：10
- 期：1
- 全文大小：1091KB
- 刊物主题：Computer Appl. in Life Sciences; Computational Biology/Bioinformatics; Data Mining and Knowledge Discovery; Bioinformatics; Algorithms;
- 出版者：BioMed Central
- ISSN：1756-0381
- 卷排序：10
文摘
BackgroundProtein relative solvent accessibility provides insight into understanding protein structure and function. Prediction of protein relative solvent accessibility is often the first stage of predicting other protein properties. Recent predictors of relative solvent accessibility discriminate against exposed regions as compared with buried regions, resulting in higher prediction accuracy associated with buried regions relative to exposed regions.