Effect of acetylcholinesterase inhibitors on AChE-Induced PrP106-26 aggregation
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  • 作者:M. V. Clos (1)
    M. Pera (1)
    M. Ratia (1)
    S. Román (1)
    P. Camps (2)
    D. Mu?oz-Torrero (2)
    L. Colombo (3)
    M. Salmona (3)
    A. Badia (1)
  • 刊名:Journal of Molecular Neuroscience
  • 出版年:2006
  • 出版时间:February 2006
  • 年:2006
  • 卷:30
  • 期:1-2
  • 页码:89-90
  • 全文大小:68KB
  • 参考文献:1. Armstrong R. A., Cairns N. J., and Lantos P. L. (2001) Spatial pattern of prion protein deposits in patients with sporadic Creutzfeldt-Jakob disease. / Neuropathology 1, 19-4. CrossRef
    2. Bartolini M., Bertucci C., Cavrini V., and Andrisano V. (2003) β-Amyloid aggregation induced by human acetylcholinesterase: inhibition studies. / Biochem. Pharmacol. 65, 407-16. CrossRef
    3. Camps P., El Achab R., Gorbic D. M., Morral J., Mu?oz-Torrero D., Badia A., et al. (1999) Synthesis, in vitro pharmacology, and molecular modeling of very potent tacrine-huperzine A hybrids as acetylcholinesterase inhibitors of potential interest for the treatment of Alzheimer's disease. / J. Med. Chem. 42, 3227-242. CrossRef
    4. Hainfellner J. A., Wanschitz J., Jellinger K., Liberski P. P., Gullotta F., and Budka H. (1998) Coexistence of Alzheimer-type neuropathology in Creutzfeldt-Jakob disease. / Acta Neuropathol. (Berl.) 96, 116-22. CrossRef
    5. Inestrosa N. C., álvarez A., Perez C. A., Moreno R. D., Vicente M., Linker C., et al. (1996) Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme. / Neuron 16, 881-91. CrossRef
    6. Tateishi J., Kitamoto T., Hashiguchi H., and Shii H. (1988) Gerstmann-Straussler-Scheinker disease: immunohistological and experimental studies. / Ann. Neurol. 24, 35-0. CrossRef
  • 作者单位:M. V. Clos (1)
    M. Pera (1)
    M. Ratia (1)
    S. Román (1)
    P. Camps (2)
    D. Mu?oz-Torrero (2)
    L. Colombo (3)
    M. Salmona (3)
    A. Badia (1)

    1. Departamento de Farmacologia, de Terapèutica, i de Toxicologia, Instituto Neurociències, UAB, Barcelona, Spain
    2. Laboratori de Química Farmacèutica, Facultat de Farmàcia, UB, Barcelona, Spain
    3. Laboratorio di Chimica e Biochimica delle Proteine, 1st di Recerche Farmacologiche Mario Negri, Milan, Italy
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