Cortisol, alpha amylase, blood pressure and heart rate responses to food intake in men aged 50鈥?0 years: importance of adiposity

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• 作者：Sisitha U Jayasinghe ; Susan J Torres ; Caryl A Nowson ; Alan J Tilbrook…
• 关键词：Food intake ; SAM system ; HPA axis ; Obesity ; Adiposity ; Men鈥檚 health ; Cortisol
• 刊名：BMC Obesity
• 出版年：2014
• 出版时间：December 2014
• 年：2014
• 卷：1
• 期：1
• 全文大小：486KB
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• 作者单位：Sisitha U Jayasinghe (1)
  Susan J Torres (1)
  Caryl A Nowson (1)
  Alan J Tilbrook (2)
  Anne I Turner (1)
  
  1. Centre for Physical Activity and Nutrition Research, School of Exercise and Nutrition Sciences, Deakin University, Burwood, VIC 3125, Australia
  2. Livestock and Farming Systems, South Australian Research and Development Institute, University of Adelaide, Roseworthy, SA 5371, Australia
  
• 刊物类别：Endocrinology; Public Health;
• 刊物主题：Endocrinology; Public Health;
• 出版者：BioMed Central
• ISSN：2052-9538

文摘

Background Increased adiposity is often associated with over activation of the hypothalamo-pituitary adrenal axis (HPA axis) and the sympatho-adrenal medullary system (SAM system) and excessive activation of these pathways in response to physiological challenges may be linked with the development of diseases. We tested the hypothesis that overweight/obese men aged 50鈥?0 years will have greater HPA axis and SAM system responses to food intake compared with age matched lean men. Lean (Body Mass Index; BMI鈥?鈥?0-25 kg/m2; n鈥?鈥?9) and overweight/obese (BMI鈥?鈥?7-35 kg/m2; n鈥?鈥?7) men (50鈥?0 years) made their own lunch using standardised ingredients at 1200 h. Concentrations of cortisol and alpha amylase were measured in saliva samples collected every 15 min from 1145 h-1400 h with the exception of during lunch (1215 h) where no sample was collected. Blood pressures and heart rate were measured at 1145 h and every 15 minutes between 1245 h and 1400 h.