Zystische Pankreastumoren

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• 作者：H. Nieß ; J. Mayerle ; M. D’Anastasi ; J. Werner
• 关键词：SchlüsselwörterPankreas ; Muzinöse und seröse Zysten ; Tumorigene Transformation ; Individuelle Therapie ; Prognose
• 刊名：Der Onkologe
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：23
• 期：2
• 页码：149-162
• 全文大小：
• 刊物类别：Medicine
• 刊物主题：Oncology;
• 出版者：Springer Medizin
• ISSN：1433-0415
• 卷排序：23

文摘

The term cystic pancreatic tumor includes heterogeneous disease of neoplastic and non-neoplastic origin, which differ markedly in terms of malignant transformation potential, treatment, and prognosis. The incidence of cystic pancreatic tumors is high. While mucinous cysts (intraductal papillary mucinous neoplasms [IPMN] and mucinous cystic neoplasms [MCN]) have a high risk of malignant transformation, serous cystic lesions generally do not. The prevalence of IPMNs in the population is currently estimated to be approximately 26 cases per 100,000. Patients diagnosed with IPMN and MCN are usually asymptomatic. MCNs, main-duct IPMN, and mixed-type IPMN should always be resected due to their high risk of malignancy. Branch-duct IPMNs also exhibit a significant risk for malignant transformation; however, the risk is lower than in other types of mucinous cystic lesions. The clinical approach in patients with branch-duct IPMNs should be determined by interdisciplinary consensus and should take into consideration patient’s individual aspects such as cyst features, patient’s age, comorbidities, and will following thorough counseling.