A review of the clinical utility of serum S100B protein levels in the assessment of traumatic brain injury
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- 作者：Eric Peter Thelin ; David W. Nelson ; Bo-Michael Bellander
- 关键词：S100B ; Traumatic brain injury ; Outcome ; Monitoring ; Screening ; Biomarker ; Serum ; Humans
- 刊名：Acta Neurochirurgica
- 出版年：2017
- 出版时间：February 2017
- 年：2017
- 卷：159
- 期：2
- 页码：209-225
- 全文大小：1765KB
- 刊物主题：Neurosurgery; Interventional Radiology; Neuroradiology; Neurology; Surgical Orthopedics; Minimally Invasive Surgery;
- 出版者：Springer Vienna
- ISSN：0942-0940
- 卷排序：159
文摘
BackgroundIn order to improve injury assessment of brain injuries, protein markers of pathophysiological processes and tissue fate have been introduced in the clinic. The most studied protein “biomarker” of cerebral damage in traumatic brain injury (TBI) is the protein S100B. The aim of this narrative review is to thoroughly analyze the properties and capabilities of this biomarker with focus on clinical utility in the assessment of patients suffering from TBI.