Visusprognose bei der Anti-VEGF-Therapie der AMD
详细信息 查看全文
- 作者：B. Book ; M. Ziegler ; B. Heimes ; M. Gutfleisch ; G. Spital…
- 关键词：SchlüsselwörterAnti ; VEGF ; Therapie ; Exudative AMD ; Visusprognose ; SD ; OCT ; Sehschärfe
- 刊名：Der Ophthalmologe
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：114
- 期：1
- 页码：49-56
- 全文大小：
- 刊物类别：Medicine
- 刊物主题：Ophthalmology;
- 出版者：Springer Medizin
- ISSN：1433-0423
- 卷排序：114
文摘
BackgroundThe efficacy of anti-VEGF therapy in exudative AMD has been established in several large clinical trials using a fixed injection regimen as well as a SD-OCT-based PRN regimen. In these studies, after the first three injections, an increase of the mean visual acuity was observed, which could be stabilized with constant treatment for up to 24 months. However, the specific course of the visual acuity is very different between individuals. The aim of the present study was to correlate specific initial SD-OCT parameters with the course of visual acuity in order to characterize factors that may be important for the individual visual prognosis.