Multiple HPV infections in female sex workers in Western Kenya: implications for prophylactic vaccines within this sub population

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• 作者：Sonia Menon ; Davy van den Broeck ; Rodolfo Rossi…
• 关键词：FSW ; HIV ; High risk HPV ; Potential high risk HPV ; Multiple pHR/HR coinfections ; Vaccine efficacy
• 刊名：Infectious Agents and Cancer
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：12
• 期：1
• 全文大小：414KB
• 刊物主题：Cancer Research; Infectious Diseases; Oncology; Tropical Medicine;
• 出版者：BioMed Central
• ISSN：1750-9378
• 卷排序：12

文摘

Background Whilst the imputed role of High Risk (HR) HPV infection in the development of cervical lesions and cancer has been established, the high number of HPV genotypes that Female Sex workers (FSW) harbour warrants that the synergistic effects of potential HR (pHR) and HR HPV genotypes be elucidated to assess the potential impact of prophylactic vaccines. This population in Kenya also harbours a number of other vaginal infections and STIs, including bacterial vaginosis (BV), trichomonas vaginalis (TV) and candida spp.