Expression of retinoic acid-binding proteins and retinoic acid receptors in sebaceous cell carcinoma of the eyelids
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- 作者：Yueh-Ju Tsai ; Shu-Ya Wu ; Hsuan-Ying Huang ; David Hui-Kang Ma…
- 关键词：Retinoic acid (RA) signaling ; Sebaceous cell carcinoma
- 刊名：BMC Ophthalmology
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：15
- 期：1
- 全文大小：2,814 KB
- 刊物主题：Ophthalmology;
- 出版者：BioMed Central
- ISSN：1471-2415
文摘
Background Sebaceous cell carcinoma of the eyelid is a malignant tumor. However, the pathoetiology of sebaceous cell carcinoma is not clear. Retinoic acid (RA) signaling is essential for skin epidermal differentiation including the eyelids. In this study, we investigate the expression of β-catenin, RA-binding proteins and RA receptors in sebaceous cell carcinoma of the eyelid and try to estimate their influence on its pathoetiology.