The Association of Brain-Derived Neurotrophic Factor Gene Polymorphism with Obstructive Sleep Apnea Syndrome and Obesity

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• 作者：Mehmet Yüksekkaya ; Nuri Tutar ; Hakan Büyükoğlan ; Munis Dündar ; İnsu Yılmaz…
• 关键词：Neurotrophins ; BDNF ; Polymorphism ; OSAS ; Obesity
• 刊名：Lung
• 出版年：2016
• 出版时间：October 2016
• 年：2016
• 卷：194
• 期：5
• 页码：839-846
• 全文大小：376 KB
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Pneumology and Respiratory System
  
• 出版者：Springer New York
• ISSN：1432-1750
• 卷排序：194

文摘

BackgroundObesity represents a major risk factor for Obstructive Sleep Apnea Syndrome (OSAS). Brain-derived neurotrophic factor (BDNF) affects the mechanisms that regulate weight, eating behavior, and metabolism. This project aims to investigate the possible association of BDNF gene polymorphism with obesity and OSAS, and to contribute knowledge to the understanding of the pathophysiology of OSAS.