Cyclin D1 in well differentiated thyroid tumour of uncertain malignant potential
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- 作者：Monika Lamba Saini ; Birgit Weynand ; Jacques Rahier ; Michel Mourad…
- 关键词：Thyroid ; Papillary carcinoma ; Follicular variant of papillary carcinoma ; WDT ; UMP ; Follicular adenomatoid nodule
- 刊名：Diagnostic Pathology
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：10
- 期：1
- 全文大小：2,096 KB
- 刊物主题：Pathology;
- 出版者：BioMed Central
- ISSN：1746-1596
文摘
Background Encapsulated follicular tumours with equivocal papillary thyroid carcinoma (PTC) type nuclear features continue to remain a challenge despite the recent attempts to classify these borderline lesions. The term ‘well differentiated tumour of uncertain malignant potential (WDT-UMP)’ was introduced to classify these tumours. The present study aimed to evaluate the role of a cell cycle regulator like cyclin D1 in these tumours along with assessment of other well established PTC markers like galectin-3, HBME-1, CK19.