Evidence of a link between resting energy expenditure and bone remodelling, glucose homeostasis and adipokine variations in adolescent girls with anorexia nervosa

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• 作者：L. Maïmoun ; S. Guillaume ; P. Lefebvre ; P. Philibert…
• 关键词：Anorexia nervosa ; Bone remodelling ; Insulin ; Leptin ; Resting energy expenditure ; Undercarboxylated osteocalcin
• 刊名：Osteoporosis International
• 出版年：2016
• 出版时间：January 2016
• 年：2016
• 卷：27
• 期：1
• 页码：135-146
• 全文大小：362 KB
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• 作者单位：L. Maïmoun (1) (2)
  S. Guillaume (3)
  P. Lefebvre (4)
  P. Philibert (5)
  H. Bertet (6)
  M.-C. Picot (6) (7)
  L. Gaspari (8)
  F. Paris (5) (9)
  M. Seneque (3)
  A.-M. Dupuys (5)
  P. Courtet (3)
  E. Thomas (10)
  D. Mariano-Goulart (1) (2)
  J. Bringer (4)
  E. Renard (11) (4) (7)
  C. Sultan (9)
  
  1. Service de Médecine Nucléaire, Hôpital Lapeyronie, Centre Hospitalier Régional Universitaire (CHRU) Montpellier et Université Montpellier 1 (UMI), 34295, Montpellier, France
  2. Physiologie et Médecine Expérimentale du Cœur et des Muscles (PhyMedExp), University of Montpellier, INSERM U1046, CNRS UMR 9214, 34295, Montpellier, France
  3. Département d’Urgence et Post-Urgence Psychiatrique, Hôpital Lapeyronie, CHRU Montpellier, UMI, INSERM U1061, 34295, Montpellier, France
  4. Department of Endocrinology, Diabetes, Nutrition, Hôpital Lapeyronie, CHRU Montpellier, 34295, Montpellier, France
  5. Departement de Biochimie et d’Hormonologie, Hôpital Lapeyronie, CHRU Montpellier, 34295, Montpellier, France
  6. Unité de Recherche Clinique et Epidémiologie, Hôpital Lapeyronie, CHRU Montpellier, 34295, Montpellier, France
  7. CIC INSERM 1411, Hôpital Saint Eloi, CHRU Montpellier, 34295, Montpellier cedex 5, France
  8. Département de Pédiatrie, Hôpital Caremeau, CHRU Nîmes, 30000, Nîmes, France
  9. Unité d’Endocrinologie et Gynécologie Pédiatrique, Département de Pédiatrie, Hôpital Arnaud de Villeneuve, 191 avenue Doyen Gaston Giraud, 34295, Montpellier Cedex 5, France
  10. Service de Rhumatologie, Hôpital Lapeyronie, CHRU Montpellier, 34295, Montpellier, France
  11. Institut de Génomique Fonctionnelle, CNRS UMR 5203/INSERM U1161/Université Montpellier, Montpellier, France
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Orthopedics
  Gynecology
  Endocrinology
  Rheumatology
  
• 出版者：Springer London
• ISSN：1433-2965

文摘

Summary Low bone mass is a consequence of anorexia nervosa (AN). This study assessed the effects of energy deficiency on various bone and hormonal parameters. The interrelationships between energy deficiency and bone remodelling, glucose homeostasis and adipokines underscore the importance of preventing energy deficiency to limit demineralisation and hormonal alterations in AN patients.