Effects of hair removal alexandrite laser on biometric parameters of the skin

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• 作者：Shiva Alavi ; Ehsan Abolhasani ; Mohammadali Nilforoushzadeh
• 关键词：Alexandrite laser ; Melanin ; Elasticity ; Insensible Water loss
• 刊名：Lasers in Medical Science
• 出版年：2016
• 出版时间：April 2016
• 年：2016
• 卷：31
• 期：3
• 页码：481-484
• 全文大小：306 KB
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• 作者单位：Shiva Alavi (1)
  Ehsan Abolhasani (1)
  Mohammadali Nilforoushzadeh (1) (2)
  
  1. Skin and Stem Cell Research Center, Tehran University of Medical Science, No 4, Maryam Dead-end Alley, South Kamraniyeh Street, Tehran, 1417653761, Iran
  2. Skin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Medicine/Public Health, general
  Dentistry
  Laser Technology and Physics and Photonics
  Quantum Optics, Quantum Electronics and Nonlinear Optics
  Applied Optics, Optoelectronics and Optical Devices
  
• 出版者：Springer London
• ISSN：1435-604X

文摘

The effects of alexandrite laser (AL) on skin parameters such as melanin content, skin layer depth, elasticity, and density have not been investigated through biometric methods. We aim to assess the effect of AL on the skin parameters through biometric devices to determine whether it has positive effects on treated region. In this pretest-posttest study, we recruited patients who attended Laser Clinic of Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran, from January through December 2014. Patients had to be free of any dermatologic conditions and lesion at the site of treatment or any contraindication to laser therapy. Baseline measurements were performed and patients received four sessions of AL therapy (spot size, 12 mm; fluence, 12 J/cm2; and pulse width, 5 Hz) with 4-week intervals. Four weeks after the last treatment session, the same parameters were assessed that included skin color, transepidermal water loss (TEWL), dermis and epidermis density and depth (through skin ultrasonography), melanin content, erythema intensity, and skin elasticity. Biometric parameters of 33 patients (27 females [81.8 %]), with mean (SD) age of 35.7 (9.5) years were evaluated. The mean percent changes of skin parameters were as follows: skin color, 5.88 % through Visioface and by 56.8 % through Colorimeter devices (became lighter); melanin content, −15.95 %; TEWL, −2.96 %; elasticity, +14.88 %; dermis depth −19.01 %; and dermis density, +1580.11 % (P < 0.001 for changes in each parameter). AL could decrease melanin content of the skin and make the skin thinner while it could increase elasticity and density of epidermis and dermis, which might indicate increased collagen content of skin.